Marchiafavae Bignami Disease in Chronic Alcoholic Patient
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 1
Abstract
Marchiafava-Bignami disease (MBD) is a rare, alcohol-associated disorder characterized by demyelination and necrosis of the corpus callosum. It is mostly seen in male alcoholics. It is caused by the combination of alcohol abuse with malnutrition, leading to metabolic, toxic, and vascular disturbances. MBD carries poor prognosis. There are 2 clinical subtypes- TYPE A where patient mainly presents with coma and stupor has a mortality of 90%; TYPE B, which of lesser severity and presents with only mild mental impairment. Clinical symptoms include reduced consciousness, psychotic and emotional symptoms, depression and apathy, aggression. Diagnosis of the disease is made on the basis of clinical findings in combination with neuro imaging. Treatment options tried include thiamine, folate and VITAMIN B12, amantadine and high dose corticosteroids have been tried with limited success. We present a patient who presented with acute onset symptoms and typical Imaging findings findings.
Authors and Affiliations
Kiran Bheemeshwar
Keywords
Related Articles
- EP ID EP502476
- DOI -
- Views 68
- Downloads 0
Rapid detection of Mycobacterium tuberculosis and Rifampicin Resistance in extra pulmonary samples using GeneXpert MTB/RIF assay
Background: GeneXpert MTB/RIF assay is efficient and reliable technique for the rapid diagnosis of extra pulmonary TB (EPTB), especially in smear negative cases. For rifampicin resistance detection, it provides accurate...
Assessment of Lipid Profile Parameters among Type II Diabetic Patients: An Institutional Based Study
Background: Diabetic patients have a greater likelihood of having dyslipidemia, hypertension, and obesity. This form of dyslipidemia remains largely undiagnosed or diagnosed late and under treated in high risk population...
In Vitro Antioxidant Activity of Methanolic Leaf Extract of Tridax Procumbens and Tithonia Diversifolia
Objective: To analyze the antioxidant activities of the methanolic leaf extract of Tridax procumbens and Tithonia diversifolia. Methods: This was done using various antioxidant models; 1,1-diphenyl-2-picryl hydroxyl (DPP...
Efficacy of Bronchial Brushing Cytology and Its Correlation with Biopsy in Lung Tumours At tertiary care Hospital northern western
Background: Bronchial brushing (BB) and the more recent trans-bronchial needle aspiration (TBNA) are well established techniques performed using flexible fiberoptic bronchoscope, for sampling trachobronchial lesions susp...
Tincture Benzoin in Dermatology
Benzoin is a drug being used since the ancient times. It is a common designation for resin obtained from a group of Styrax trees. The chief constituents of benzoin resin are benzoin, cinnamic acids and their esters.It is...