Marrow Iron Status and its Correlation with Serum Ferritin in Anaemia of Chronic Kidney Disease
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 11
Abstract
Anemia, a common entity in Chronic Kidney Disease can increase the morbidity and mortality. This study was done to determine the haematological profile and bone marrow stores in patients with anemia of CKD and also to study the usefulness of serum ferritin as a single screening tool for assessing the status of body iron stores. 35 patients with chronic Kidney disease and a hemoglobin level less than l0g/dl were assessed in this study. Their sociodemographic details and aetiology of the disease was noted. Reports of Hemogram, Peripheral smear and other investigations like Blood urea, Serum creatinine, Serum calcium, Uric acid, Serum albumin, Serum Ferritin etc were also noted. Glomerular filtration rate was estimated using the Cockcroft Gault Formula. Bone marrow aspiration was done and the aspirate was semi quantitatively graded for its iron content. Data collected was entered in Microsoft excel 2010 and analysed. It was found that 60 % were males and common causes were diabetes mellitus and hypertension. 45.7% had hypochromic microcytic anemia. Mean creatinine and blood urea were 9.8 mg/dl and 163 mg/dl respectively. A Normocellular marrow was seen in majority of cases. A significant correlation was seen between serum ferritin level and bone marrow iron status. It was concluded that serum ferritin estimation can be used as a screening test to detect the iron status in patients with anemia of Chronic Kidney Disease
Authors and Affiliations
Dr Aruna R
Keywords
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