Massive Intra-Tumor Hemorrhage during Induction Chemotherapy in Neuroblastoma: A Case Series Report
Journal Title: Journal of Cancer Sciences - Year 2017, Vol 4, Issue 1
Abstract
We describe 5 children with high risk neuroblastoma (NB) who, during the induction phase of therapy, were admitted with circulatory shock because of massive intra-tumor bleeding. Patient’s intensive supportive care with fluid resuscitation, blood and blood product’s transfusion succeeded to restore hemodynamic stability. Surgical intervention to control bleeding was necessary in two of the children. All children survived the massive hemorrhage to continue their treatment as per protocol. Overall prognosis was not affected by this incident.
Authors and Affiliations
Abeer Al-Diab
Keywords
Related Articles
- EP ID EP246878
- DOI 10.13188/2377-9292.1000015
- Views 123
- Downloads 0
NOTCH1 Activation Depletes the Pool of Side Population Stem Cells in ATL
Background: HTLV-I infection is associated with the development of adult T-cell leukemia (ATL), a malignancy characterized by a highrate of disease relapse and poor survival. Previous studies reported the existence of si...
Rectifying the Epigenetic Field Defect in Gastric Carcinogenesis
Gastric cancer is undoubtedly a fatal malignancy worldwide with high incidence and dismal prognosis. Its formation and development can be driven by genetic defects, dietary factors, alcohol consumption, viral infection,...
Association of Hepatitis C with Hepatocelluar Carcinoma: A Cross-Sectional Study from Northern Pakistan
Aim:Hepatocellular Carcinoma (HCC) is one of the most deleterious among cancer types which is associated with high morbidity and mortality. The disease more commonly affects men usually in their fifth and sixth decade of...
HTLV-I Tax-Mediated Inactivation of Cell Cycle Checkpoints and DNA Repair Pathways Contribute to Cellular Transformation: “A Random Mutagenesis Model”
To achieve cellular transformation, most oncogenic retroviruses use transduction by proto-oncogene capture or insertional mutagenesis, whereby provirus integration disrupts expression of tumor suppressors or proto-oncoge...
Evaluation of Prostate CancerDetection Rates in PatientsUndergoing TransrectalUltrasound (TRUS) GuidedProstate Biopsy
Background: Prostate cancer is one of the most common types of organ cancer among males in Turkey as well as all over the world. The gold standard method for histopathological diagnosis of prostate cancer is Trans rectal...