Maternal and Fetal Outcome in Deranged Liver Function Test and Jaundice Complicating Pregnancy: A Prospective Study
Journal Title: Journal of Advanced Research in Medicine - Year 2018, Vol 5, Issue 3
Abstract
Background: The objective of the study was to study maternal and fetal outcome in pregnancy complicated with deranged liver function test and jaundice. Methods: Total 150 antenatal patients with clinical or laboratory evidence of abnormal liver function test and jaundice were selected for study done for a period of one-and-half year at a tertiary care hospital in north India. Results: All cases were in their third trimester of pregnancy out of which 93.3% were unbooked cases. Most of the patients presented with pregnancy induced hypertension, fever and jaundice at time of admission. Other presenting complaints were nausea, vomiting, pedal edema, abdominal pain and including 3 cases of altered sensorium. Acute viral hepatitis was most important cause of jaundice in this study followed by preeclampsia and ICP were other causes of jaundice in this study. Hepatitis B was the most common cause of acute hepatitis (26.7%) followed by hepatitis C (6.7%). Maternal mortality was seen in 4 cases (3 cases of Eclampsia & HELLP syndrome and one case of multi-organ failure). 138 patients were kept in ICU for intensive monitoring. Preterm delivery was most common maternal complication. Of all the deliveries, 26.7% were preterm, 31(21%) were IUFD, 57(38%) had fetal distress with meconium stained liquor, 27 (18%) had PROM, 50 (33%) had fetal growth restriction. Conclusions: Deranged liver function and jaundice in pregnancy results in a very high perinatal as well as maternal morbidity and mortality, and requires an early diagnosis and intensive care management.
Authors and Affiliations
Dr. Shalini Shakarwal,
Keywords
Related Articles
- EP ID EP362527
- DOI 10.24321/2349.7181.201814
- Views 100
- Downloads 0
Acute Phase Treatment for Prevention of Coronary Artery Stenosis Caused in Kawasaki Disease: A Single Center Retrospective Study
Background: The acute phase treatment to prevent coronary artery stenosis have not been established in Kawasaki disease (KD). Objective: To ascertain the outcomes of coronary artery lesions (CAL) in patients who received...
Chronic Constipation due to Hypercalcemia Associated with Parathyroid Adenoma: An Uncommon Presentation - A Brief Report
Constipation is a very common problem and many a times its cause remains obscure. We present a case of 55-year old women who presented with chronic constipation. Physical examination was essentially normal. Investigation...
New Oral Anticoagulants: An Overview
Oral anticoagulant therapy is used in the prevention and treatment of venous thromboembolism (VTE), prevention of stroke and other systemic emboli in patients with atrial fibrillation (AF) and artificial heart valves. V...
The Prevalence of Transfusion-Transmitted Infections (TTIs) and Distribution Pattern of ABO Rh Blood Group in Blood Donors and Possible Correlation of TTIs with ABO and Rh Blood Groups – A Study at RBTC (North-West) Delhi
Hepatitis B, Hepatitis C and HIV infections represent global health problems of significant magnitude. There are studies and hypothesis which suggest that genetic predispositions like ABO and Rh blood group may affect oc...
Acute Phase Treatment for Infants Younger Than 1 Year of Age with Kawasaki Disease: A Single Center Retrospective Study
Background: Infants younger than 1 year of age with Kawasaki disease (KD) have a high risk for coronary artery lesions (CAL). However, the appropriate acute phase treatment for the infants has not been established. Objec...