MATERNAL LIPID METABOLISM AND ITS IMPLICATIONS FOR FETAL GROWTH
Journal Title: World Journal of Pharmaceutical Research - Year 2019, Vol 8, Issue 3
Abstract
Glucose is the most abundant nutrient crossing the placenta and the use of both glucose and amino acids by the fetus is essential to sustain intrauterine development. Nevertheless, changes in lipid metabolism during gestation also play a key role in the development of fetal fat mass and subsequent growth. During early pregnancy there is an increased accumulation of fat depots in the mother, which is switched to an active adipose tissue breakdown in late pregnancy; these changes are responsible for the maternal hyperlipidemia that is normally present during the last third of pregnancy. The changes are controlled by different hormones, but the biphasic changes in insulin sensitivity taking place during pregnancy seem to play a major role. Maternal hyperlipidemia mainly results from an increase in TAG-rich lipoproteins, which transport LCPUFA in particular mainly in their esterified form. Lipoproteins in maternal plasma don’t cross the placenta directly, but the presence of lipoprotein receptors, fatty acid binding proteins and different lipases allow the transfer of LCPUFA to the fetus.
Authors and Affiliations
Rajiha Majid Abdulateef
Keywords
Related Articles
- EP ID EP671911
- DOI -
- Views 103
- Downloads 0
A REVIEW OF ANTI – CANCER DRUGS IN SIDDHA LITERATURES FOR YONI PUTTRU (CERVICAL OR VAGINAL CANCER)
Hundreds and thousands of people develop cancer every year. This present paper is about the compilation of Siddha preparations for Yoni puttru (Cervical or vaginal cancer) mentioned in various Siddha text books and also...
A PHARMACOGNOSY STUDY OF WRIGHTIA TINCTORIA PLANT
Wrightia tinctora is a tree widely used by the peoples of Tamil Nadu as a traditional medicine for pain and inflammations. Latex form the plant especially from leaves is directly applied on inflammation. This plant is ve...
KNOWLEDGE AND ATTITUDE TOWARDS PSORIASIS AMONG ADULT SAUDI POPULATION IN MAKKAH AL-MUKARRAMAH, SAUDI ARABIA 2017
Objectives: To assess the awareness and knowledge about Psoriasis in Makkah Al-mukarramah among Saudi adult population. Subjects and methods: It is a Cross-sectional descriptive study among the adult Saudi population in...
A CRITICAL ANALYSIS OF AYURVEDIC HERBS USED IN VAATSHLESHAMIK JWARA W.S.R. TO SWINE FLU
Major concept of aurveda is prevention and cure of a disease by natural ways. In Ayurveda it is said that pragyapradh is the main cause of janpadodhwans (epidemic/pandemic disease). In August 2010, the World Health Organ...
A CONCEPTUAL STUDY OF PRISHTHA GATA MARMA
The term marma means pran, jiva or life. It can be explained as sandhisthanam or jeevasthanam. Marma are the meeting place of five elements of the body namely- Mamsa, Sira, Snayu, Asthi and Sandhi. These are the vital ar...