Mathematical analysis of corneal remodelling after intracorneal ring surgery in keratoconus

Journal Title: International Journal of Ophthalmology - Year 2017, Vol 10, Issue 3

Abstract

"AIM: To represent mathematically the intersection between the ectatic corneal geometry and the plane of intracorneal ring implants (ICRS) in order to determine the corneal response to ICRS surgery in keratoconus (KC). Thereafter, to present the concept and early results of a newly derived topography-guided nomogram for ICRS surgery for the treatment of keratectasia. METHODS: The corneal rings plane intersection was modelled to a conic section. Ring effect was the result of: the ring size, position (steep vs flat), location (distance from the geometric centre of the cornea), and the discrepancy between the ring’s curvature and the tunnel’s curvature. Femtosecond laser was used to create the tunnels and the incision sites were chosen according to the nomogram in order to place the thickest ring in the steepest portion of the cornea regardless of the astigmatism axis of refraction. RESULTS: The conic section had a more prolate shape in the steep area of the cornea than in the flat area, depending on the corneal sagittal curvature. Equal ring size had more flattening effect in the steep area than in the flat area. Thick segment should be implanted under the steep portion of the cornea regardless of the cylinder axis of refraction. Single segment in the steep area was sufficient in early and moderate cases of KC. The new nomogram provided more topographic regularity with significant reduction of astigmatism and better improvement in uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA) than the conventional nomogram. CONCLUSION: The newly derived nomogram can produce better results than the conventional nomogram. Moreover, based on this concept, a new nomogram can be integrated into the femtosecond laser software to create topography-guided, customized, elliptical tunnels with modified focal asphericity that allows for customized focal flattening of the irregularly steepened ectatic cornea."

Authors and Affiliations

Elias F Jarade

Keywords

Related Articles

Placido disk-based topography versus high-resolution rotating Scheimpflug camera for corneal power measurements in keratoconic and post-LASIK eyes: reliability and agreement

"AIM: To compare the repeatability/reproducibility of measurement by high-resolution Placido disk-based topography with that of a high-resolution rotating Scheimpflug camera and assess the agreement between the two instr...

Influence of polymorphisms in VEGF, ACE, TNF and GST genes on the susceptibility to retinopathy of prematurity among Chinese infants

"AIM: To investigate common polymorphisms in VEGF, ACE, TNF and GST genes with retinopathy of prematurity (ROP) risk among Chinese infants. METHODS: Nine polymorphisms in the above genes were genotyped on 724 advanced ca...

Treatment of myopic foveoschisis via macular buckling and vitrectomy

The aim of the present study was to evaluate the efficacy and safety of the treatment of myopic foveoschisis patients using the macular buckling with L-shaped titanium plate and silicon sponge combined with vitrectomy. T...

Expressions of matrix metalloproteinases 1 and 3 and their tissue inhibitors in the conjunctival tissue and fibroblasts cultured from conjunctivochalasis

"AIM: To investigate the expression of matrix metalloproteinases 1 and 3 (MMP-1 and MMP-3) and their tissue inhibitors of metalloproteinases 1 and 3 (TIMP-1 and TIMP-3) in the conjunctiva of eyes with conjunctivochalasis...

Prevalence of amblyopia among preschool children in central south China

"AIM: To determine the prevalence and factors associated with amblyopia among children aged 30-83mo in central south of China. METHODS: A population-based, cross-sectional study was conducted in children aged 30-83mo in...

Download PDF file
  • EP ID EP610049
  • DOI 10.18240/ijo.2017.03.04
  • Views 53
  • Downloads 0

How To Cite

Elias F Jarade (2017). Mathematical analysis of corneal remodelling after intracorneal ring surgery in keratoconus. International Journal of Ophthalmology, 10(3), -. https://europub.co.uk/articles/-A-610049