Mathematical Modeling using Pure Fractions and Monte Carlo Simulation to Control Thalassemia Disease Transition

Abstract

Thalassemia is one of the most widely spread genetic disease, especially in the Middle East. The study aims to create a mathematical model for the control of the transition of genetically inherited thalassemia disease. New form of representing the numbers in the unit - interval [0, 1] which is called pure fractions and the theory and properties of pure fractions were examined and applied. To generalize the effectiveness of this innovative model to predict the number of generations needed to eliminate Thalassemia or other similar genetic diseases, Monte-Carlo Simulation via MATLAB was used. Results indicated such genetic diseases could be controlled and can be eliminated with proper family policies.

Authors and Affiliations

Abdelrahim M Zabadi

Keywords

Related Articles

Production and Simple Purification of Recombinant Human Granulocyte Colony-Stimulating Factor using the Inteintag in Escherichia Coli

Background: Granulocyte colony-stimulating factor (G-CSF) is a cytokine which have many functions such as stimulating of hematopoiesis, proliferation and differentiation of granulocyte progenitor cells and production of...

The Use of Medical Devices in Italy And Europe: The Need Of A Careful Control Policy

The use of medical devices is in continuous expansion and constitutes a valid aid to ailing people, due to remarkable technological advances. The regulation on their circulation in Italy and Europe are inspired by the pr...

Endemic Opisthorchis Felineus Infection Limits Changes of Individual with Mutant Cyp1a1 and Gstm1 Genes to be Effectively Involved in Oil Field Working in the North of Siberia

More than 90% of the population of the north of Siberia (Russian Federation) inhabiting near oil field sites is infected with the endemic helminth of Opisthorchis felineus. We demonstrated that the oil industry workers w...

Genetic Control and Phytohormonal Regulation of Plant Embryogenesis

The review is devoted to genetic mechanisms of regulation of plant embryonic development. Numerous families of genes identified to date that control this phase of plant ontogenesis are presented in detail; their key role...

Screening of Five and Six-Membered Nitrogen-Containing Heterocyclic Compounds as New Effective Stimulants of Linum Usitatissimum L. Organogenesis in Vitro

Linum usitatissimum L. (flax or linseed) is one of the oldest economically important crops used in biotechnology as a source for bioactive compounds. Flax fiber and seed have industrial significance as a source of cellul...

Download PDF file
  • EP ID EP325423
  • DOI 10.19070/2379-1020-170009
  • Views 76
  • Downloads 0

How To Cite

Abdelrahim M Zabadi (2017). Mathematical Modeling using Pure Fractions and Monte Carlo Simulation to Control Thalassemia Disease Transition. International Journal of Medical Biotechnology & Genetics (IJMBG), 5(1), 52-56. https://europub.co.uk/articles/-A-325423