Determination of ammonia concentrations in cirrhosis patients-still confusing after all these years?

By the end of the nineteenth century, ammonia had been identified as the main factor responsible for hepatic encephalopathy syndrome. Ammonia is one of the principal products of hepatic metabolism and high concentrations...

Greater Celandine hepatotoxicity: a clinical review

Herbal hepatotoxicity is a rare and poorly described disease because reported cases are mostly scattered and lack an appropriate causality assessment. We now describe in detail the clinical picture of herbal hepatotoxic...

Hepatitis C virus infection in health-care settings: Medical and ethical implications

Hepatitis C is a major public health issue. It infects about 200 million people worldwide and is a major cause of chronic liver disease. Its transmission in medical facilities is a topic of increased concern, as outbreak...

Potential Molecular Targets of Statins in the Prevention of Hepatocarcinogenesis

Hepatocellular carcinoma (HCC) represents 90% of liver tumors. Statins, may reduce the incidence of various tumors, including HCC. Antitumoral activities may be mediated by changes in transforming growth factor-beta (TGF...

Ironing out steatohepatitis