Mean Platelet Volume in Patients with Acute Ischemic Stroke: A Case Control Study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 7
Abstract
Background: Cerebrovascular diseases (CVD) include some of the most common and devastating disorders. The important risk factors are hypertension, heart disease, atrial fibrillation, diabetes mellitus, cigarette smoking, and hyperlipidemia. In this context platelets play a crucial role in the pathogenesis of atherosclerotic complications, contributing to thrombus formation. Platelet size found to be elevated in individuals with hypertension and diabetes mellitus. Platelet size (mean platelet volume, MPV) is a marker and possibly determinant of platelet function. Aims & Objectives: To determine mean platelet volume (MPV) and it’s correlation with Ischemic stroke/TIA and role in severity of stroke. Material and Methods: The study was a prospective case-control study conducted at tertiary care centre Jabalpur, including 50 cases and 50 controls. Results: In this study MPV was found to be higher in older age group among cases and control.MPV is found to be higher in patients of Ischemic stroke as compare to controls. Comparing cases and control with respect to smoking shows significant high MPV among cases who smoke. Maximum no. cases with hypertension had MPV 9-10.9 fl. This finding is statistically significant suggesting that hypertension is associated with high MPV. Total 12 cases had MPV 11-12.9 with higher Rankin severity score (RSS). Conclusion: Mean platelet volume (MPV) as a risk factor in cases of coronary artery disease is well known.MPV is higher in patients of acute ischemic stroke / TIA and is associated with more severe morbidity in patients with acute ischemic stroke / TIA
Authors and Affiliations
Dr Tarunendra Kumar Mishra
Keywords
Related Articles
- EP ID EP517505
- DOI -
- Views 91
- Downloads 0
Association between Vitamin- D Deficiency and Stroke - A Comparative Study
Objective: To determine the serum levels of 25-OH Vitamin-D in both ischemic as well as hemorrhagic stroke patients and to determine the magnitude of Vitamin-D deficiency in the study group. To compare Vitamin-D deficien...
Mitral Leaflet Separation Index (MLSI): A Step Ahead to Assess Severity of Mitral Stenosis in Patients with Atrial Fibrillation
Objective: Evaluation of the severity of mitral stenosis using mitral leaflet separation index and its significance over planimetry and pressure half time method especially in patients with Atrial fibrillation. Material...
Designing Antimicrobial Peptide: Current Status
Antimicrobial peptides (AMPs) are critical part of the human natural immunity, innate specifically, which is found among all modules of life. These peptides, which are produced by leukocytes, are working as broad-spectru...
Comparative Study of Laura Mitchell’s Physiological Relaxation Technique Versus Jacobson’s Progressive Relaxation Technique on Severity of Pain And Quality of Life in Primary Dysmenorrhea: Randomized Clinical Trial
Aim: To Evaluate which relaxation technique is more effective on severity of pain and quality of life in primary dysmenorrhea. Objectives: To compare the effect of Laura Mitchell’s physiological versus Jacobson’s progres...
Self-directed E-Learning in Under Graduate Medical Teaching
Introduction: E-learning or internet based learning, in various forms, is being implemented as a teachinglearning method and is hypothesized to replace traditional learning methods. In this context, there are questions r...