Mean Variance Relationships of Genome Size and GC Content
Journal Title: Annual Research & Review in Biology - Year 2015, Vol 7, Issue 4
Abstract
The present article focuses how the genome size and GC content are explained based on codon and amino-acid usage. This current study aims to identify the statistically significant factors of genome size and GC content using statistical modeling. The present analyses show that habitat (P = 0.08), taxonomy (P = 0.02), genome GC content (P < 0.01), isolation temperature (P< 0.01), GC% of the 2nd position within a codon for protein coding part (P< 0.01), number of total tRNA genes within genome (P< 0.01), lower (P< 0.01) and upper (P = 0.01) boundary of GC% for tRNA encoding genes, average frequency (within 100) of non-polar aliphatic (P< 0.01), aromatic (P< 0.01), and positively charged r group containing amino acids (P< 0.01) are statistically significant effects of entire genome size. On the other hand, taxonomy (P = 0.03), genome size (P< 0.01), isolation temperature (P = 0.02), GC% of protein coding part of total genome (P< 0.01), GC% of the 1st (P< 0.01), 2nd (P< 0.01), and 3rd position (P< 0.01) within a codon for protein coding part, number of total tRNA genes within genome (P< 0.01), lower (P< 0.01) and upper (P< 0.01) boundary of GC% for tRNA encoding genes, average frequency (within 100) of non-polar aliphatic (P< 0.01), aromatic (P< 0.01) and negatively charged r group containing amino acids (P = 0.01) are statistically significant effects of entire genome GC content. These analyses support, and also try to remove some conflicts of many earlier research findings. However, the present analyses also have identified all new causal factors in the variance models, and many additional causal factors in the mean models of genome size and genome GC content, which was not reported by the earlier investigators.
Authors and Affiliations
Sunil Kanti Mondal, Rabindra Nath Das, Sudip Kundu, Jinseog Kim, Gurprit Grover, Shamim Akhtar Ansari
Keywords
Related Articles
- EP ID EP353458
- DOI 10.9734/ARRB/2015/16709
- Views 105
- Downloads 0
Influence of Treatment Parameters on Symptom Relief in Individuals with Vitamin B12 Deficiency
Objective: Ever-growing numbers of displeased vitamin B12 deficiency patients are joining online support groups seeking help. The current study attempted to assess, quantitatively, several of the concerns of these patien...
Seminal Plasma Levels of Neutral Alpha Glucosidase Activity and Its Interactions with Spermiogram in Nigerian Males
Introduction: Seminal neutral alpha glucosidase activity is a useful parameter in determination of the cause of azoospermia, This has often been reported to have seasonal variation and has not been extensively studied in...
Isolation of Parasites from Black Tiger Prawn; Peneaus monodon from Isaka River, Okirika Local Government Area, Rivers State, Nigeria
Aims: To determine the parasitic fauna, site-specificity of the parasites in the host and the parasite load in relation to length, weight and sex of P. mondon. Study Design: The study is a survey using prawns from Isaka...
Stimulation of Hepatocytes Repair by Fruit Juice of Opuntia ficus indica in Anti Cancer Drug Cyclophosphamide (CP)-Induced Liver Toxicity in Mice
Cyclophosphamide (CP) is a cytotoxic alkylating agent that has been used extensively in medicine as anti neoplastic agent for the treatment of different cancers worldwide. Chemotherapy with CP is associated with signific...
Tannins and Saponins in Two Tropical Legumes and Measurement of their Biological Activity
Aims: Raw tropical legumes have abundant amounts of tannins and saponins which are usually eliminated with high temperature once they are cooked. These biomolecules may represent new alternatives, to allopathic medicine,...