Measurement of Blood Lead in Patients with First Trimester Abortion
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 9
Abstract
Background: Blood lead has been associated with an elevated risk ofmiscarriage.Theplasmaticfraction of lead represent the toxicologically active fraction of lead.Women with tendency to have a higher plasma lead for a given whole blood leadratio could tend toward an elevated risk of miscarriageand would consequently have history of spontaneous abortion. Objectives :The main objective of this study is to evaluate the role of plasma / whole blood lead ratio as a cause of Abortion in the first trimester. Patients and Methods: We studied 50 pregnant women in the first trimester who developed spontaneous abortion and 50 women with normal pregnancy as a controlwith matching in gestational age taken betweenfrom January 2014 to September2014.All studied women were taken from Baghdad hospital in Medical City .Criteria for inclusion in this study were patient with spontaneous abortion, and measured their plasma and whole blood lead ratio by inductivelycoupled plasma mass spectrometry. The study excluded any woman with risk of spontaneous abortion for another causes or any pregnant woman with gestational age more than14 week G.A Results: There was significant correlation between plasma whole blood lead ratio and risk of abortion were( P= 0.003) which is highly significant and the result divided into 3 tertile according to level of plasma /whole blood lead ratio. Also itfound a significant relationship withplasma lead and the risk of abortion(P= 0.009) with no significant correlation with whole blood lead ( P= 0.284 ). Conclusions :Women with a large plasma/whole blood lead ratio may be at higher risk of miscarriage, which could be due to a greater availability of placental barrier–crossing lead
Authors and Affiliations
Maaed. M. Shalal, Ficog. Ishraq. M. Kadhim, Nada Saed Abbas, Fibgo. Vianh. Al-Mansi
Keywords
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- EP ID EP255438
- DOI 10.9790/0853-1609012630
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