Measurement of Fat Content in the Human Body by Nuclear Magnetic Resonance Methods
Journal Title: Obesity Research - Open Journal - Year 2017, Vol 4, Issue 1
Abstract
Aim: Characteristics of adipose tissue in the human body reflect the specifics of metabolism in the body, and therefore present an interest for the medical diagnostics. It is useful to apply the methods that allow to get such information non-invasively, namely with the help of high resolution nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI). Material and Methods: In the present study, we have implemented such techniques by using the 0.5-Tesla MRI scanner Bruker Tomikon S50. Processing MRI images was carried out using graphical tools of ImageJ software. Results: Measurements of fat content in the human body by NMR spectroscopy were carried out on the 0.5 T MRI scanners. The NMR spectra were obtained from the separate parts of the body and then combined. The peaks of water and fat were determined in this composite spectrum. Their analysis provided information about the content of fat in the human body. To spatially select the scanned volume, we applied the methods of local NMR spectroscopy with the use of non-uniform (gradient) fields. We then compared spectral data with the average density of the body for each study subject, as well as with the volume of fat found from the MR images. The correlation between these parameters was established. Conclusion: There is an inverse relationship between the average body density and the fat-towater ratios obtained from spectroscopy (IF/IW) and MRI (VF/V) data. For any person, the correlation between the real body fat percentage and the ratio of water and fat peaks from the whole-body NMR spectra takes place.
Authors and Affiliations
Yury A. Pirogov
Keywords
Related Articles
- EP ID EP553879
- DOI 10.17140/OROJ-4-129
- Views 163
- Downloads 0
Coenzyme Q10, Glucose Homeostasis and the Probable Mediating Role of Adipokines
Coenzyme Q10 is one of the most popular nutritional supplements, which has been discovered in 1955. It is also known as ubiquinone, Q10, CoQ and vitamin Q10. This coenzyme has two isoforms; the oxidized form, ubiquinone,...
Adipocytokines: A Potential Link Between Obesity and CNS Disorders
The interrelationships between obesity and high fat mass with different chronic pathophysiological conditions have been taken into consideration in recent decades along with the growing prevalence of obesity. Epidemiolog...
Impacts of Lifestyle and Socioeconomic Status on Childhood Obesity
Childhood obesity is an important indicator to predict adulthood obesity, so monitoring factors that contribute to childhood obesity plays a constructive role in preventing adulthood chronic diseases and metabolic syndro...
Obesity and Clozapine Use in Schizophrenia
Introduction: Schizophrenia is a chronic mental disorder, and treatment is based on the use of antipsychotics, such as clozapine. These drugs have been associated with obesity and metabolic changes. Objective: A systemat...
Effective Intervention Strategies Combining Mediterranean Diet and Exercise for Reducing Obesity, Metabolic and Cardiovascular Risks in High-Risk Populations: Mini Review
The global rise in obesity and cardiovascular disease is not showing any sign of slowing down, and effective health interventions may provide an important part of the solution. Whilst comprehensive evidence about the hea...