MECHANISMS OF THE DEVELOPMENT OF IMPAIRED CONSCIOUSNESS IN PATIENTS WITH TRAUMATIC BRAIN INJURY AND MAXILLOFACIAL TRAUMA
Journal Title: International scientific journal Science and Innovation - Year 2024, Vol 3, Issue 3
Abstract
The ineffectiveness of existing methods of treatment of impaired consciousness of traumatic etiology indicates that the mechanisms of development of impaired consciousness in patients with CCI have not yet been clarified. Purpose: to study the mechanisms of development of impaired consciousness in patients with CCI. Materials and methods: thorough clinical and neurological, laboratory (early screening markers of coma: leukocytosis, hyperglycemia and acidosis), ECG, chronographic, Echo ES, EEG, TCD and MSCT of the brain were performed in 124 patients (80 men, 54 women) with various form of CCI. Analysis of the data obtained shows that the molecular mechanism of impairment of consciousness is depression of intracellular energy synthesis. IIE synthesis, developed as a result of cerebral ischemia. And the severity of the oppression of consciousness is proportional to the intensity of the decrease in intracellular energy synthesis.
Authors and Affiliations
Abdullaev Afzal Sarhadovich, Usmanov Rakhmatillo Fayzullaevich
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