Mediastinal Tuberculosis Lymphadenitis during Anti-TNF Therapy - Case Report
Journal Title: Archives of Clinical Gastroenterology - Year 2015, Vol 1, Issue 1
Abstract
Tuberculosis is described during the use of monoclonal antibodies against tumour necrosis factor (TNF) for Crohn’s disease treatment. We report a case of a 44 year old man that developed fever, night sweats and weight loss during immunosuppressive and anti-TNF therapy for Crohn’s disease. After extensive investigation we performed mediastinoscopy with biopsy of the paratracheal lymph node. A histopathological study revealed caseous necrosis. The patient improved after therapy against tuberculosis. During anti-TNF therapy, the diagnosis of tuberculosis may be mainly difficult when an atypical location is present. Clinical skills are important mainly in countries where tuberculosis is endemic.
Authors and Affiliations
da Silva Bruno César, Vosqui Nascimento Fábio Carneiro, Oliveira Lisboa Sonyara Rauedys, Gonçalves Ramos Eduardo Antônio, Surlo Valdiana Cristina, Galvão Nonato Alves Tatiana Senna, Santana Genoile Oliveira
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- EP ID EP325345
- DOI 10.17352/2455-2283.000008
- Views 99
- Downloads 0
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Mediastinal Tuberculosis Lymphadenitis during Anti-TNF Therapy - Case Report
Tuberculosis is described during the use of monoclonal antibodies against tumour necrosis factor (TNF) for Crohn’s disease treatment. We report a case of a 44 year old man that developed fever, night sweats and weight lo...