Medical line of treatment versus surgical approach in the treatment of chronic peptic ulcer
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 5
Abstract
Peptic ulcer disease was one of the major cause of morbidity and mortality until the last decades of the 20th century. In resent time epidemiological trends started to point to an impressive fall in its incidence due to. the discovery of effective and potent acid suppressants and antibiotics against Helicobacter pylori. The main aim and objective of this study is to compare between, conservative medical lines of treatment versus surgical approach in treatment of chronic peptic ulcer. The present clinical study was carried out at surgical wards of Subbaiah Institute of Medical Sciences and Research Centre, in the period of March 2014 to March 2015. Patients were selected based on inclusion and exclusion criteria’s. Following selection of patients, they were subjected to medical line of treatment for 2-3 months with Omeprazole 40mg, Amoxicillin 1550mg / Clarithromycin 500mg and Tinidazole 1000 mg (7days course in a month repeated for 2 months) and the cases were followed up for varying length of time. Among 15 cases, 10 cases were treated successfully with medical line of management. One case had anterior duodenal ulcer perforation for which emergency laparotomy and closure of perforation was done and other 4 cases underwent posterior gastrojejunostomy with bilateral truncal vagatomy for peptic ulcer complications like deformed duodenal cap and early signs of pyloric stenosis. The incidence of surgery in recent years for chronic Peptic Ulcer Disease has reduced because of advent of proton pump inhibitors and H2 receptor blockers and combination drugs with antibiotics which proved effective against Helicobacter pylori infection. Keywords: Peptic ulcer disease, Gastrojejunostomy
Authors and Affiliations
Arun kumar RV, Mohan SVS, Dr. Nagashree
Keywords
Related Articles
- EP ID EP372711
- DOI -
- Views 54
- Downloads 0
Osmotic Fragility Index and Stability of Human Erythrocytes in the Presence of Four Oral Antiretroviral Drugs
The relative stability of human erythrocyte membrane in the presence of four oral antiretroviral drugs was investigated in vitro. Blood collected by venipuncture from 60 confirmed healthy humans were used for the study....
To Assess the Efficacy of Honey in Comparison with 1% Silver Sulfadiazine Cream as A Burn Wound Dressing in Superficial and Partial Thickness of Burns
Aim of this prospective randomized comparative study was to evaluate the efficacy of honey and silver sulfadiazine cream in the management of superficial and partial thickness of burns. This prospective randomized study...
Prevalence of STEC O157 in paediatric diarrhoeas and evaluating efficacy of SMAC and O157 antigen detection in the diagnosis of O157 E.coli
Abstract: Shiga toxin producing Escherichia coli (STEC) is an important group of E. coli that can cause severe diarrhoea and many food borne outbreaks worldwide. STEC is known to be associated with large scale outbreaks...
A Review on Control Methods for Bacteriological Water Quality and Biofilm in Dental Unit Water Systems
Contamination of dental unit water systems (DUWS) to a variety of microorganisms and biofilm formation is one of the most important problems in dentistry centers against the proper operation of thisunits. This study was...
Management of Supracondylar Fractures of the Humerus in Children: Conservative versus Operative
Abstract: Supracondylar fractures of the humerus are the most common fracture pattern of the elbow in children. Severely displaced supracondylar fractures of the distal humerus in children are challenging problems. Ma...