Melioidosis: An emerging infection in India
Journal Title: Indian Journal of Microbiology Research - Year 2017, Vol 4, Issue 2
Abstract
Introduction: Melioidosis is caused by Burkholderia pseudomallei which is endemic in South East Asia. Lack of proper microbiological services in many countries results in under-reporting of cases and the global burden of infection remains underestimated. This is a study to analyse the clinical presentation and risk factors for melioidosis in India. Materials and Method: A retrospective study was carried out on ten culture proven cases of melioidosis in a tertiary care hospital in South India between January 2009 and December 2014. Result: Ten cases were studied in five years of which nine were males. They had varying clinical presentations like loss of weight and loss of appetite(10%), fever(60%), headache(10%), abdominal pain(20%), joint pain(10%), weakness of limbs(10%), swelling of thigh(20%) and faecal and urinary incontinence((10%). The risk factors included diabetes mellitus (100%), alcohol consumption(90%)and tuberculosis(30%). All the isolates were sensitive to Ceftazidime, Piperacillin-tazobactam, Imipenem, Cotrimoxazole, Amoxycillin-clavulanate and Meropenem while only 80% were sensitive to Ciprofloxacin. Of the 10 cases, two expired and the rest responded to treatment. Conclusion: Melioidosis is an emerging infection in India especially in males and diabetes and alcoholism are identified as the commonest risk factors. Control of the disease requires close monitoring, improved clinical laboratory standards and aggressive therapy.
Authors and Affiliations
Sathya Bhama MC, Saritha N, Jyothi R
Keywords
Related Articles
- EP ID EP294904
- DOI 10.18231/2394-5478.2017.0040
- Views 62
- Downloads 0
Extent of antimicrobial resistance in Acinetobacter species in a Tertiary Care Teaching Hospital
Acinetobacter, gram negative coccobacillus, has become a frequent pathogen in hospitals and other health care settings. Acinetobacter species cause a wide variety of illness in debilitated and hospitalized patients espec...
Aerobic Bacteriological Profile from Wound Site Infections in Road Traffic Accident (RTA) Patients
Background: Infections of musculoskeletal injuries due to road traffic accidents, especially open fractures, continue to pose a challenge. There is limited information on the early bacterial contaminants of these wounds...
Detection of metallobetalactamase producing imipenem resistant acinetobacter species in intensive care unit patient in a Tertiary Care Centre
Introduction Metallobetalactamase producing Acinetobacter species has been reported to be an important cause of nosocomial infection and is a critical therapeutic problem worldwide especially in the intensive care unitOb...
Occurrence and characterization of urinary tract infection in patients with and without diabetes mellitus with special reference to Escherichia coli
Introduction: The urinary tract is the second most common site for infection next to respiratory tract and urinary tract infection (UTI) occurs more frequently in persons with diabetes mellitus. The factors affecting UTI...
Microbial etiology of acute gastroenteritis in pediatric patients in Western India
Introduction: Acute gastroenteritis is a major cause of illness and death among infants and young children worldwide. According to the World Health Organization (WHO), an estimated 2.5 billion cases of diarrhea occur amo...