Membrane Stabilizing and Antioxidant Activity of Myrica esculenta Leaves Extracts
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2018, Vol 4, Issue 5
Abstract
Abstract:In the present study, different extracts of leaves of Myrica esculentawere prepared and evaluated their membrane stabilizing and antioxidant effects. All extract were tested for presence of phytoconstituents i.e., alkaloid, carbohydrate, sterols, proteins, amino acids, saponin, and phenolic compounds. Membrane stabilizing effect was studied by hypotonic solution induced haemolysis of erythrocyte and Antioxidant activity was studied by DPPH method at a different concentration. From the study, Phytochemical analysis showed that methanol extract was the richest extract for the tested phytoconstituents. Maximum membrane stabilizing activity of leaves of Myrica esculentashowed in Methanol extract (61.11±1.10) at a concentration of 1000 μg/ml in comparison to standard drug aspirin. From antioxidant studies, methanol extract showed maximum antioxidant activity (91.36±1.27) at a concentration of 1000 μg/ml than other extract and comparison to standard drug ascorbic acid. From above studies it could be concluded that methanol extract showed maximum membrane stabilizing and antioxidant activities. Keywords:Myrica esculenta; erythrocyte membrane stabilization; anti-inflammatory; antioxidant; DPPH; aspirin; ascorbic acid.
Authors and Affiliations
Deepak Kumar, Ashwani Sanghi, Shefali Arora, Gaurav Tiwari, Raju Chandra
Keywords
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