Membrane Stabilizing Effect and Antioxidant Potential of Different Extracts from Eicchornia crassipes Flowers: An In Vitro Assessment
Journal Title: Tropical Journal of Natural Product Research - Year 2018, Vol 2, Issue 1
Abstract
Received 29 November 2017 Revised 24 December 2017 Accepted 27 December 2017 Published online 07 January 2018 Eicchornia crassipes has been traditionally used as a tonic for the skin of horses, for irritation and inflammation. The aim of this study was to evaluate the total phenolic and flavonoid contents, antioxidant and membrane stabilizing activities of different extracts from E. crassipes. In vitro antioxidant activity was determined by DPPH radical scavenging, ABTS radical scavenging, hydroxyl radical scavenging and reducing power assays. The total flavonoid and phenolic contents were also investigated. Membrane stabilizing potential of the extracts was studied on human erythrocytes in hypotonic solution and by heat-induced hemolysis procedures. Quantitative analysis revealed the highest amount of total phenols and flavonoids in the ethanol extract while the lowest amount was in the ethyl acetate extract. Ethanol extract exhibited promising antioxidant potential in the DPPH, ABTS, and hydroxyl radical scavenging assays compared to the other extracts. Also, the ethanol extract possesses strong reducing power ability compared to the other extracts. A significant correlation was found between the antioxidant activity of the extracts and their total phenolic and total flavonoid contents. The ethanol extract exhibited the highest percentage hemolysis inhibition in hypotonic solution-induced hemolysis and in heat-induced hemolysis procedures. Results from this study showed that the flowers of E. crassipes exhibited in vitro antioxidant and anti-inflammatory activities. This study substantiated the folkloric use of E. crassipes flowers in inflammatory disord
Authors and Affiliations
Prasanth M. Kumar, Venkatesan Suba, Rami B. Reddy Reddy, Srinivasa P. Babu
Keywords
Related Articles
- EP ID EP489331
- DOI 10.26538/tjnpr/v2i1.5
- Views 56
- Downloads 0
https://www.tjnpr.org/viewarticle.aspx?articleid=50
There is a growing concern of the potential risk of producing genetically defective sperm and transmitting germ-line mutations to progeny by fathers who prefer their children at old age. Men with male factor infertility...
Isolation and Characterization of Antibacterial Metabolites Produced by Streptomyces species from Escravos River, Delta State, Nigeria
The isolation of Streptomyces sp that yields bioactive molecule is of significant importance in the advancement of new metabolite to combat pathogen. Water, soil and sediment samples were obtained from Escravos River, De...
Microscopic Features and Preliminary Thin Layer Chromatography of “Thanh ngam” (Picria fel-terrae Lour. ex Wall) Collected in Viet Nam
Picria fel-terrae Lour. ex Wall, a plant belonging to the family Scrophulariaceae, is a medicinal plant in Vietnamese traditional medicine which has long been used to treat anorexia, snake bite wound and help gastrointes...
Antimalarial Activity of the n-Butanol Fraction of Uapaca togoensis (Pax) Stem Bark in Mice
The stem bark extract of Uapaca togoensis has been used in traditional medicine for the management of fever, epilepsy, fatigue and rheumatism. This study was aimed at evaluating the in vivo antimalarial activity of the n...
Natural Product Synthesis and Drug Discovery: Shortcomings and Successes
Natural products have evolved over the years and several of them have been found to interact with biological macromolecules in intact organisms. Their structural complexity often makes it difficult to produce natural dru...