MEMBRANOUS NEPHROPATHY IN PREGNANCY- A CASE REPORT AND REVIEW OF LITERATURE
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2017, Vol 5, Issue 4
Abstract
Nephrotic syndrome occurs in 0.012-0.025% of all pregnancies. Membranous nephropathy is a major cause of nephrotic syndrome in adults (30-40%). We present a case of idiopathic membranous nephropathy (IMN) diagnosed during pregnancy. Pregnancy was complicated by the development of intrauterine growth restriction of fetus and oligohydramnios. Labour was induced at 36 weeks of gestation because of premature rupture of membranes. Patient delivered a female baby weighing 2 kg. The commonest presentation of idiopathic membranous nephropathy is nephrotic syndrome with preserved renal function. Nephrotic range proteinuria is abnormal for any trimester of pregnancy and needs evaluation by renal biopsy. Mainstay of treatment of IMN during pregnancy are steroids. Immunosupppressants used during pregnancy are cyclosporine and tacrolimus. Anticoagulation during pregnancy and postpartum should be considered.
Authors and Affiliations
Sushruti Kaushal, Poojan Dogra, Kapil Malhotra, Tanupriya Tanupriya, Reena Sharma, Anil Kumar
Keywords
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