Mesenchymal Stem Cells in the treatment of Cerebral Ischemic Injury

Journal Title: Global Journal of Animal Scientific Research - Year 2014, Vol 2, Issue 2

Abstract

Mesenchymal stem cells (MSC) are undifferentiated adult stem cells capable of self-renewal and differentiation with a broad tissue distribution essential for tissue repairing and maintenance. These cells are isolated and expanded in vitro and kept as stem cells throughout many generations while maintaining its capability of differentiation when receiving appropriate stimuli. They have intrinsic multilineage potential, and as such, under special experimental conditions, are capable of differentiating into neuronal and glial cells, both in vivo and in vitro. The MSC migrate to the injured site after being intravenously injected, and in there promote endogenous cell proliferation, diminish apoptosis, and reduce the neurological deficitsresulting from cerebral ischemia. In this review we describe the many actions that the MSC exert on the injured nervous tissue, through their direct, paracrine, and systemic effects.

Authors and Affiliations

Nilton B. A. Junior, Ricardo J. Del Carlo, Lukiya S. C. Favarato, Vanessa G. Pereira, Aline R. Murta, Betânia S. Monteiro, Daise Nunes Queiroz da Cunha

Keywords

Related Articles

Influence of Some Factors on Composition of Dromedary Camel Milk in Sudan

The present study was carried out to investigate the impact of management systems, breeds, parity and stage of lactation on milk composition of Sudanese Arabi camels. Samples of camel milk were collected from 120 heal...

Weight Gain and Economic Implications of Feeding Uda Rams with Graded Levels of Dietary Mineral Salt (Potash) in Tullun Gwanki Grazing Reserve, Silame Local Government Area, Sokoto State, Nigeria.

The study was conducted to examine weight gain and economic implications of feeding Uda rams with graded levels of dietary mineral salt (potash) in TullunGwanki Grazing Reserve, Silame Local Government Area, Sokoto Sta...

Body Morphometric of Goat Local Race Destined to Slaughtering in Madagascar.

Agroclimatics and range management process have zootechnic performances effects on Ruminants production (cattle, sheep and goat). During three months within centers of slaughtering in peripheric Capital zone, a populat...

Pelt Pattern Classification of New Born Lambs Using Image Processing and Artificial Neural Network

In this study a method to determine the pelt pattern of Zandi sheep lambs using image processing and neural network is presented. Data were collected from Zandi sheep breeding center located in the North East of Tehran...

Effect of Dietary Inclusion of Gum Arabic (Acacia senegal) on Performance and Blood Chemistry of Broiler Chicks.

The aim of this study was to investigate the effect of feeding graded levels of gum Arabic (0%, 2.5%, %5 and 7.5%) on the performance and blood chemistry of broiler chicks. A total of 192 unsexed broiler chicks (Cobb...

Download PDF file
  • EP ID EP29029
  • DOI -
  • Views 395
  • Downloads 5

How To Cite

Nilton B. A. Junior, Ricardo J. Del Carlo, Lukiya S. C. Favarato, Vanessa G. Pereira, Aline R. Murta, Betânia S. Monteiro, Daise Nunes Queiroz da Cunha (2014). Mesenchymal Stem Cells in the treatment of Cerebral Ischemic Injury. Global Journal of Animal Scientific Research, 2(2), -. https://europub.co.uk/articles/-A-29029