Mesenteric Microcystic/Reticular Schwannoma: A Diagnostic Dilemma
Journal Title: Journal of Krishna Institute of Medical Sciences University - Year 2016, Vol 5, Issue 1
Abstract
Microcystic/reticular schwannoma is a rare variant of schwannoma with a predilection for visceral locations including the gastrointestinal tract. Due to overlapping features with other tumours, unawareness of this tumour type may lead to diagnostic pitfalls. We here report a case of microcystic/reticular schwannoma arising in the mesentery of a 25-year-old female. The tumour was incidentally discovered by ultrasonography. An operation was performed and histological examination revealed a capsulated tumour composed of spindle cells with reticular pattern set within a myxoid stroma. Differential diagnoses were Extra Gastrointestinal Stromal Tumour (EGIST) with myxoid change, microcystic/reticular schwannoma, Low-Grade Fibromyxoid Sarcoma (LGFMS) and Aggressive Angiomyxoma (AAM). Immunohistochemically, the tumour cells were positive for S-100 protein which was consistent with a peripheral nerve sheath tumour. Albeit very rare, microcystic/reticular schwannoma should be included in the differential diagnosis of mesenteric tumours. The awareness and the knowledge about this rare tumour are needed to achieve the correct diagnosis.
Authors and Affiliations
Sandhya S. Ware , Dilip S. Sarate , Ajay D. Jungare , Vinod K. Sawaitul
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