Metabolic therapy in the comprehensive treatment of patients with comorbidity of chronic pancreatitis and stable coronary artery disease

Journal Title: Гастроентерологія - Year 2017, Vol 51, Issue 1

Abstract

Metabolic therapy is one of the few ways to restore normal functions of all the vital organs and systems. The goal of the research was to explore the effectiveness of a course of treatment using metabolic drug Vazonat (meldonium dihydrate) to correct prooxidant-antioxidant and trophological disorders in patients with comorbid course of chronic pancreatitis (CP) and stable coronary artery disease (SCAD). The study included 90 patients with CP in combination with SCAD, who were divided into two groups (depending on the treatment program): I group (45 patients) received conventional treatment (CT); group II (45 patients) in addition to CT received Vazonat as follows: 5 ml intravenous bolus injection 1 time a day for 10 days followed by administration of 1 capsule (250 mg), 2 times per day for one month. It has been shown that the addition of Vazonat to the treatment of patients with comorbidity of CP and SCAD is more conducive to improving the performance and trophological prooxidant-antioxidant status than the standard basic therapy.

Authors and Affiliations

L. S. Babinets, N. A. Melnyk

Keywords

Related Articles

Chronic inflammatory bowel diseases: epidemiological features in Ukraine

Background. The number of registered patients with inflammatory bowel diseases (IBD) that is characterized by systemic manifestations and polymorbidal course is increasing nowadays. IBD, which include ulcerative colitis...

Cytokine Status in Children with Chronic Gastroduodenal Pathology

Actuality. Diseases of the stomach and duodenum in children tend to continual growth, and the pathology itself is characterized by a group of features that are absent in adults. Aim: to identify the features of blood ser...

Assessment of Proteinase-Inhibitory System and Plasma Fibrinolytic Activity in Patients with Gastroesophageal Reflux Disease and Diabetes Mellitus Type 2

Aim: investigation of proteinase-inhibitory system and plasma fibrinolytic activity in patients with gastroesophageal reflux disease (GERD) combined with diabetes mellitus (DM) type 2. Methods. The study involved 112 pat...

Histometric Features of Endocrine Islets of the Pancreas in Chronic Pancreatitis

Long-existing chronic pancreatitis (CP) in the last stages of development leads to the destruction of the endocrine pancreatic tissue, but the mechanisms of these changes are not well understood. The aim of the study was...

Current Options for Improvement of Treatment of Gastroesophageal Reflux Disease

The article is dedicated to the treatment of one of the most common pathologies in gastroenterology — gastroesophageal reflux disease. The use of proton pump inhibitors and their combination with prokinetics is being dwe...

Download PDF file
  • EP ID EP212795
  • DOI 10.22141/2308-2097.51.1.2017.97867
  • Views 86
  • Downloads 0

How To Cite

L. S. Babinets, N. A. Melnyk (2017). Metabolic therapy in the comprehensive treatment of patients with comorbidity of chronic pancreatitis and stable coronary artery disease. Гастроентерологія, 51(1), 16-21. https://europub.co.uk/articles/-A-212795