Metaplastic Carcinoma Breast with Chondroid Differentiation: A Rare Case Report and Review of Literature
Journal Title: National Journal of Laboratory Medicine - Year 2017, Vol 6, Issue 3
Abstract
Metaplastic carcinoma of the breast is a rare tumour. Though metaplastic carcinoma is by itself a rare entity, however metaplastic carcinoma with chondroid differentiation makes it even rarer. These tumours are ER, PR, HER2 negative (triple negative) and portend poor prognosis. Present case is of 30 years female presented in Surgery Department with painless lump in upper outer quadrant and was advised ultrasonography. Ultrasonography revealed a neoplastic lesion. Her modified radical mastectomy was done and specimen was send to the Department of Pathology. Specimen measures 12 x 12 x 3 cm in size. On cutting a grey white, firm mass, measuring 2 x 2 x 1.5 cm was noted. On microscopy the diagnosis of metaplastic carcinoma with chondroid differentiation was made which was further confirmed by IHC showing ER, PR and HER2 negative and positivity for EGFR, CK5/6 and S100.
Authors and Affiliations
Dr. Vishal Dhingra, Dr. Priya Singh, Dr. Yamini Jindal, Dr. Varsha Kumar, Dr. Faheema Hasan
Keywords
Related Articles
- EP ID EP377344
- DOI 10.7860/NJLM/2017/24248:2238
- Views 109
- Downloads 0
Role of Line Probe Assay for Rapid Detection of Mycobacterium tuberculosis Complex and Drug Resistance Directly from Clinical Samples
ABSTRACT Introduction: The global burden of Multi Drug Resistant Tuberculosis (MDR TB) is increasing worldwide. Smear microscopy has low sensitivity, culture based tests for identification of tubercle bacilli and drug su...
Detection of Anti-ABO Antibodies Titres Prior ABO Incompatible Renal Transplantation using Indirect Antihuman Globulin Test via Tube Incubation and Gel Column Technique
Introduction: Renal transplantation is the ideal treatment for patients with End Stage Renal Disease (ESRD). Nowadays, ABO incompatible renal transplant give encouraging results. It reduces the waiting time of patients o...
Average Values of Neutrophil Lymphocyte Ratio among a Representative Sample of Adult Population in a Tertiary Care Teaching Hospital
Introduction: Several studies have been conducted over the years for a simple, reliable, cost effective investigation to know the intensity of systemic inflammation in patients suffering from shock, major surgery, sepsis...
AIDS Dementia Complex with Tinea Faciei with Very Low CD4 Count: An Unusual Case Report
ABSTRACT Dermatophyte infections are common in HIV infected patients and can occur at some point during their illness but Tinea faciei not a common presentation in adults, although a few cases have been described in HIV-...
Cell Block- A Useful Adjunct in Cytopathology of Serous Effusions
Introduction: Use of the Cell Block (CB) technique in cytology increases the diagnostic accuracy. This technique enables cells to be retrieved in a fluid specimen to form a paraffin block, which concentrates the cells in...