Metaplastic Carcinoma Breast with Chondroid Differentiation: A Rare Case Report and Review of Literature
Journal Title: National Journal of Laboratory Medicine - Year 2017, Vol 6, Issue 3
Abstract
Metaplastic carcinoma of the breast is a rare tumour. Though metaplastic carcinoma is by itself a rare entity, however metaplastic carcinoma with chondroid differentiation makes it even rarer. These tumours are ER, PR, HER2 negative (triple negative) and portend poor prognosis. Present case is of 30 years female presented in Surgery Department with painless lump in upper outer quadrant and was advised ultrasonography. Ultrasonography revealed a neoplastic lesion. Her modified radical mastectomy was done and specimen was send to the Department of Pathology. Specimen measures 12 x 12 x 3 cm in size. On cutting a grey white, firm mass, measuring 2 x 2 x 1.5 cm was noted. On microscopy the diagnosis of metaplastic carcinoma with chondroid differentiation was made which was further confirmed by IHC showing ER, PR and HER2 negative and positivity for EGFR, CK5/6 and S100.
Authors and Affiliations
Dr. Vishal Dhingra, Dr. Priya Singh, Dr. Yamini Jindal, Dr. Varsha Kumar, Dr. Faheema Hasan
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