Methicillin-resistant Staphylococcus aureus among patients in a teaching hospital in Ghana
Journal Title: International Journal of One Health - Year 2017, Vol 3, Issue
Abstract
Aim: This study determined the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) and assessed the resistance profiles of strains. Materials and Methods: Inpatients and outpatients of all age groups presenting with sepsis as well as skin and soft tissue infections were screened from October 2006 to March 2007. Resistance to methicillin (oxacillin) and other relevant antibiotics was determined by the Kirby-Bauer disk diffusion and minimum inhibitory concentration (MICs) by the E-test (AB, Biodisk, Solna, Sweden). Results: Methicillin resistance was 34.8% (87/250), majority (67/87) of which were hospital acquired MRSA. Resistance was 100% to the β-lactams, 78.2% to cotrimoxazole, 75.8% to tetracycline, 59.8% to gentamicin, 56.3% to flucloxacillin, 34.4% to erythromycin, and 32.2% to cefuroxime. MIC ranged from 4-256, 0.125-256, 0.064-32, and 1.5-32, respectively, to oxacillin, gentamicin, cotrimoxazole, and ceftriaxone. Conclusion: Prevalence of MRSA is high in Komfo Anokye Teaching Hospital, and routine surveillance should be put in place to monitor the epidemiology of this pathogen.
Prevalence and risk factors of brucellosis in man and domestic animals: A review
Brucellosis is the most common worldwide zoonosis with 500,000 new cases every year in humans and infections in millions of animals. This infection is mainly acquired by humans through consumption of unpasteurized milk a...
Mingling of human and veterinary strains of Staphylococcus aureus: An emerging issue in health-care systems
Aim: Methicillin-resistant Staphylococcus aureus remains a leading cause of hospital and community infections. We report a retrospective molecular characterization of S. aureus strains from different settings: hospital w...
Prevention, detection, and response to anthrax outbreak in Northern Tanzania using one health approach: A case study of Selela ward in Monduli district
Background: Anthrax is an infectious fatal zoonotic disease caused by Bacillus anthracis. Anthrax outbreak was confirmed in samples of wild animals following rumors of the outbreak in wild animals, livestock, and humans...
The importance of timely introduction of vancomycin therapy against methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and severity of MRSA bacteremia at Teaching Hospital, Anuradhapura, Sri Lanka
Aim: Worldwide, an estimated 2 billion healthy people carry Staphylococcus aureus (SA) and of these, up to 53 million are thought to carry methicillin-resistant SA (MRSA). MRSA bacteremia patients are more critical to ma...
Emergence of extended spectrum beta-lactamases-producing strains belonging to cefotaxime-M-1 class from intensive care units patients and environmental surfaces in Pakistan
Aim: The emergence of multidrug-resistant (MDR) bacteria is the most dangerous threat for the treatment of infectious diseases. The aim of this study was to detect and characterize extended spectrum beta-lactamases (ESBL...