METHOD FOR CORRECTING METABOLIC AND IMMUNOPATOLOGICAL DISORDERS IN CHILDREN WITH EXOGENOUS CONSTITUTIONAL OBESITY
Journal Title: International scientific journal Science and Innovation - Year 2024, Vol 3, Issue 3
Abstract
The results of our own study of weight correction, metabolic and immunopathological disorders in overweight and obese adolescent children are presented. Aim: Development of a treatment and preventive program for weight correction, metabolic and immunopathological disorders in overweight and obese children. Materials and methods: 60 adolescents were examined: 40 with exogenous constitutional obesity of the first degree, 20 with overweight. Studies were carried out on the levels of adiponectin, highly sensitive C-reactive protein, lipid spectrum in the blood plasma, as well as bacteriological examination of feces. The developed treatment and preventive program was applied to 50 children, divided into 4 groups: the main ones - 20 obese children (1) and 10 overweight children (2), who received a course of probiotic medication as part of the developed treatment and preventive program. The control groups included 20 obese children (3) and 10 overweight children (4), who, for a number of reasons (parental abandonment, child abandonment, financial situation in the family), did not receive a probiotic drug as part of the weight correction program. The results were assessed after 6 and 12 months, with repeated paraclinical studies. Results: Assessment of the level of CRP-hs after 12 months of application of the developed treatment and prophylactic program demonstrated a decrease in the activity of CRP-hs and an increase in the level of adiponectin (from 4.06 ± 0.06 to 2.4 ± 0.03 and from 5.0 ± 0 .13 to 12.23±0.08 mg/ml, respectively), a significant (p <0.05) decrease in total cholesterol levels (from 6.09±1.07 to 4.85±0.93 mmol/l) and triglycerides (from 2.05±0.17 to 1.12±0.29 mmol/l), as well as normalization of the quantitative and qualitative composition of the intestinal microbiota, the degree of dysbiotic disorders and the disappearance of signs of bacterial contamination in the main groups of children, compared with the control in groups. Stabilization of body weight, disappearance of signs of metabolic and immunopathological disorders after 12 months of use of the developed treatment and preventive program in the complex treatment of obesity allow us to recommend its use in both group and individual treatment.
Authors and Affiliations
Guzaliya Khasanova
Keywords
Related Articles
- EP ID EP734040
- DOI 10.5281/zenodo.10814882
- Views 31
- Downloads 0
PSYCHOLOGICAL PECULIARITIES OF SOCIAL ADAPTATION IN PARANOID SCHIZOPHRENIA
The high prevalence of schizophrenia in combination with the progressive course of this disease leads to a gradual increase in the specific cognitive, emotional motivational and voluntary changes of the individual, a sig...
SOME FEATURES OF IMMUNE STATUS INDICATORS IN SCHOOL CHILDREN OF JIZZAKH REGION OF RUz SUFFERING ALLERGIC DISEASES
The need to study the effects of environmental factors on humans is constantly increasing due to the changing environmental and industrial environment. Due to the intensive development of various industries, a significan...
ORBITAL COMPLICATIONS IN RHINOSINUSITIS IN YOUNG CHILDREN
In the course of the study, the features of orbital complications in rhinosinusitis in young children were studied. A patient admitted to the ENT department of TashPMI clinic with a diagnosis of left-sided acute purulent...
ETHICAL IDEALS IN FORMING SPIRITUAL-MORAL QUALITIES OF FUTURE DOCTORS
This article discusses the role of moral ideals in the formation of moral and ethical qualities of future doctors, professional ethics, and moral and educational events organized outside the auditorium
THE EFFECTIVENESS OF TRICHOGRAMMA DENDROLIMI AGAINST THE YPONOMEUTA MALINELLUS ZELL
This article presents the results of the biological efficacy of Trichogramma dendrolimi when used against eggs of the apple moth-Yponomeuta malinellus Zell. The experiments were conducted in the “Aim-2” department of the...