Method for determining 1,2:3,4-diepoxybutane in workplace air
Journal Title: Medycyna Pracy - Year 2016, Vol 67, Issue 5
Abstract
Background: 1,2:3,4-Diepoxybutane (DEB) is a substance classified to a group of carcinogens. The maximum admissible concentration (MAC) value for this substance in workplace air is not specified in Poland. Due to the fact that DEB has been used in domestic companies there is a need to develop a sensitive method for determining 1,2:3,4-diepoxybutane in the work environment. Material and Methods: The studies were performed using gas chromatography (GC) technique. An Agilent Technologies chromatograph, series 7890A, with a mass selective detector (5975C, Agilent Technologies, USA) was employed in the experiment. Separation was performed on a capillary column with Rtx-5MS (30 m × 0.25 mm × 0.25 μm) (Restek, USA). Results: The developed method consists in passing the known volume of air through sorbent tube filled with activated carbon, desorpting the DEB vapor with dichloromethane/methanol mixture (95:5, v/v) and analyzing the obtained solution. The method is linear (r = 0.999) within the investigated working range of 0.09–2.06 μg/ml, which is equivalent to air concentrations of 5–114 μg/m3 for a 18 l air sample; limit of detection (LOD) − 9.89 ng/ml and limit of quantification (LOQ) − 29.67 ng/ml. Conclusions: The described analytical method enables selective determination of 1,2:3,4-diepoxybutane in the workplace air in the presence of 1,3-butadiene, 1,2-epoxypropane, toluene, styrene and 1,2-epoxy-3-phenoxypropane. The method is characterized by good precision and accuracy and meets the criteria for measurement of chemical agents, listed in PN-EN 482:2012. Med Pr 2016;67(5):645–652
Authors and Affiliations
Joanna Kowalska, Anna Jeżewska
Keywords
Related Articles
- EP ID EP282775
- DOI 10.13075/mp.5893.00415
- Views 149
- Downloads 0
Prevention of the musculoskeletal system’s dysfunction based on the example of Prevention Program of Spinal Pain Syndrome in Nursing Staff
Background: Most of the medical activities, which are work-related, both static and dynamic are performed by nurses in a forced position. Excessive and improper strain of the musculoskeletal system, especially when lifti...
ASSESSMENT OF MUSCULOSKELETAL LOAD IN REFUSE COLLECTORS
Background: The aim of this work was to assess the load on the musculoskeletal system and its effects in the collectors of solid refuse. The rationale behind this study was to formulate proposals how to reduce excessive...
LEGAL ASPECTS OF WORKERS' HEALTH PROTECTION AGAINST ASBESTOS IN POLAND IN THE LIGHT OF THE EU LEGAL FRAMEWORK
Legal protection of human life and health against asbestos dust-related hazards is carried out in various dimensions of the European Union law mainly focused on health protection of employees and responsibilities of empl...
Humor at Work Questionnaire – Polish adaptation of Humor Climate Questionnaire (HCQ)
Background: The aim of the paper is to present the Polish adaptation of the Humor Climate Questionnaire (HCQ), designed to measure humor as organizational climate feature. Material and Methods: The authors employed back-...
KRZTUSIEC JAKO CHOROBA ZAKAŹNA PRACOWNIKÓW OCHRONY ZDROWIA - PRZYPADEK KLINICZNY Z KOMENTARZEM
W pracy omówiono zmieniającą się w ostatnich latach sytuację epidemiologiczną krztuśca ze zwróceniem uwagi na przeniesienie zachorowań z małych dzieci na starsze grupy wiekowe - młodzież i dorosłych. Zachorowania mogą do...