Methotrexate induced sprue- like disease in a psoriatic patient: A rare case report
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2016, Vol 2, Issue 11
Abstract
Abstract: “Drug – induced” or “medication- related” forms of enteropathy are known to result in alterations in small intestinal architecture and function causing “sprue- like” mucosal changes, diarrhoea and malabsorption. Many drugs are proved to induce these changes and these include chemotherapeutic agents like colchicine, vincristine, and immunosuppresants like methotrexate, azathioprine, mycophenolate mofetil [1]. Several cases of villous atrophy following use of immunosuppresants are reported. But, literature search revealed only two cases of intestinal villous atrophy secondary to methotrexate [2]. We present this third case of sprue- like syndrome secondary to methotrexate treatment in a psoriatic patient. Keywords: methotrexate, sprue- like enteropathy
Authors and Affiliations
Arundhathi. S, Sunitha. S, Anil Malleshi Betigeri
Keywords
Related Articles
- EP ID EP389105
- DOI -
- Views 110
- Downloads 0
Investigation of Antiallergic and Antipruritic Activity Studies of Shorea robusta Oleoresin and Wrightia tinctoria Bark Extracts by Animal Models
Plants have formed the basis of sophisticated traditional medicinal systems that have been in existence for thousands of years and continue to provide mankind with new remedies. The study of total ethanol extract of Shor...
A Study of the Efficacy of Atorvastatin Alone and Its Combination with Omega-3 Fatty Acids in Patients with Hyperlipidemia
Atherosclerosis is one of the major causes of increased morbidity and mortality associated with coronary artery disease, cerebrovascular accidents, and peripheral vascular diseases. Dyslipidemia is one of the important c...
A Study of the Sinu-atrial Nodal Artery in the Nepalese Cadavers
Abstract:Cardiac problems are encountered in the clinic more nowadays. Many of the cardiac problems and procedures have impact on the Sinu-atrial nodal arterywhich is the pace-maker of the heart. Variations of Sinu-atria...
Pattern of Serum Creatinineand Urea in Patients Seen with Symptoms of Bladder Outlet Obstruction
Abstract: Bladder outlet obstruction (BOO) is a major urological condition characterized by impedance of urine outflow from the bladder into the urethra. The causes are numerous and commoner in aging males. The result is...
The Possible Antigenotoxic Potential of Ginger Oil on Etoposide–Treated Albino Rats
Abstract: Etoposide is an anticancer drug that belonging to topoisomerase II inhibitors, it used to treat various human malignancies. Ginger (Zingiberofficinale) is a medicinal plant belonging to the familyZingiberaceae....