Micro anatomy of pelvi ureteric junction and its changes in hydronephrosis
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH - Year 2017, Vol 9, Issue 2
Abstract
The concept of the pelvi ureteric junction has been there for more than a century and yet there is no clear anatomical definition of this junction. Pelvi ureteric junction (PUJ) obstruction is an impedance to the urine flow from the renal pelvis to the ureter. It occurs in 1:1000 to 2000 newborns and is the commonest cause of obstructive uropathy in children.1 The pathophysiology of pelvi ureteric junction obstruction in unknown. The knowledge of histologic changes and innervations at UPJ is necessary for proper understanding of patho physiology and its correlation with the functional outcome after pyeloplasty. This systematic review addresses the question of whether the human pelvi ureteric junction is a discrete anatomical entity and changes seen in PUJ obstruction. Methods: A systematic literature review was undertaken to investigate the normal gross and microscopic anatomy of the pelvi ureteric junction and histopathological changes at pelvi ureteric junction in patients with PUJ obstruction using the electronic databases MEDLINE, PubMed, Cochrane Library and Google Scholar
Authors and Affiliations
Pradyumna Pan
Keywords
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