Microballoons: A better approach for gastro retention
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2014, Vol 2, Issue 2
Abstract
The purpose of this review is to accumulate the recent study on floating drug delivery system with special emphasis on microballoons as drug delivery. Microballoons are emerging as the most promising drug delivery as it overcome many limitations of conventional drug delivery system. As microballoons delivery system provides longer retention in gastric pH, hence longer is the residence time and therefore enhance the solubility of drugs that are less soluble in high pH environment. The formation of cavity inside the microsphere depends upon the preparation temperature and the surface smoothness determines the floatability and the drug release rate of the microballoons. The review includes the classification, advantages, disadvantages, method of preparation and future aspects of microballoons. Basic anatomy and physiology of stomach is also studied.
Authors and Affiliations
Rakhi Negi| Department of pharmaceutics, Division of pharmaceutical sciences, Shri guru ram rai institute of technology and science, Patelnagar Dehradun, 248001 India, Laxmi Goswami| Department of pharmaceutics, Division of pharmaceutical sciences, Shri guru ram rai institute of technology and science, Patelnagar Dehradun, 248001 India, Preeti Kothiyal| Department of Pharmacology, Division of pharmaceutical sciences, Shri guru ram rai institute of technology and science, Patelnagar Dehradun, 248001 India
Keywords
Related Articles
- EP ID EP14154
- DOI -
- Views 394
- Downloads 23
Pharmacognostical and Pharmacochemical Parameters of Tablet Sutashekhara Rasa – Without Gold
Tablet Sutashekhara Rasa (TSR) is an Ayurvedic, herbo-metal formulation prescribed widely for several conditions such as Acid peptic disorders, Pain in abdomen, Haemorrhage, Mental disorders etc. On analysis of pharmco...
Analysis of position of greater palatine foramen in central Indian adult skulls: a consideration for maxillary nerve block
Quantitative reckoning of embelin from fruits of Embelia tsjeriam- cottam using water bath process as an alternate method of extraction
The world is culturally endowed with various forms of healing practices having rich medical wisdom of immense importance. One of such pharmacognostically indispensable medicinal plant is Embelia tsjeriam-cottam A. DC....
UV Spectrophotometric Method development for Capecitabine in Eudragit and Chitosan based Microspheres and its Validation
A simple, rapid, accurate, precise, and economic Spectrophotometric method for Capecitabine in bulk and formulated microspheres dosage form has been developed. Capecitabine shows absorbance maximum at different waveleng...
Capparidaceous Medicinal Plants of North-West Rajasthan: Good Sources of Ascorbic Acid
Ascorbic acid contents of roots, shoots and fruits of three selected medicinal plants like Capparis decidua, Cleome gynandra and Cleome viscosa of family Capparidaceae have been analysed. Maximum ascorbic acid contents...