Microbiological profile and antibiotic susceptibility pattern of uropathogens in Anand district of Gujarat, India.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2015, Vol 4, Issue 4
Abstract
Background: Antimirobial drug resistance in urinary tract pathogens is a challenging problem to the medical practitioners & important reason for increased morbidity and healthcare expenditure. Aim/Objective: To document prevalence of pathogens in Urinary Tract infections (UTIs) and their current antimicrobial susceptibility pattern in Anand region of Gujarat, India. Materials and Methods: Urine samples from symptomatic UTI cases were processed. Bacterial isolates were identified using standard methods and AST was performed by disc diffusion methods as per CLSI guidelines (2012). Results: A total of 954 consecutive urine specimens from symptomatic UTI cases were processed.378 samples showed significant bacteriuria. Antimicrobial susceptibility pattern of isolates were studied for 26 different antimicrobials of different classes. Among uropathogens isolated, E.coli was found predominant (51.9%) followed by Klebsiella spp (18.3%), Pseudomonas spp (17.2%), Proteus spp (3.2%), S. saprophyticus (2.6%) Enterobacter spp (1.3%), Providencia spp (05%), Yeast (3.2%), Staphylococcus aureus (1.6%) and Alcaligenes spp (0.3%). Out of antimicrobials tested Ampiillin (92.3%), Cefpodoxime (89.3%), Amoxyclave (84.7%), Piperacillin (84.4%) and Cefotaxime (83.6%), Ceftazidime (73.8%) have shown highest resistance by different uropathogens. Aminoglyciosides, Carbapenem and 3rd/4th generation fluroquinolones showeded low resistance. Conclusion: E.coli was found to be the most dominant uropathogen in this region, prevalence of Pseudomonas spp was also found comparatively higher. There has been a fairly high levels of drug resistance among the uropatogens isolated.
Authors and Affiliations
Nilofar R. Sodagar| Research Scholar - M.Sc (MLT), Pramukhswami Medical College, Karamsad., Dr. Sunil S. Trivedi| Ph.D. (Microbiology), Prof. in Microbiology and Principal of Smt. L. P. Patel Institute of MLT, Pramukhswami Medical College, Karamsad.
Keywords
Related Articles
- EP ID EP3590
- DOI -
- Views 417
- Downloads 24
THE ASSOCIATION OF ki67 PROLIFERATION MARKER WITH ESTROGEN, PROGESTERONE AND HER2 MARKERS AMONG SUDANESE FEMALES WITH BREAST CANCER
Background: Breast cancer aggressiveness can be correlated with proliferation status of tumor cells, which can be ascertained with tumor grade and Ki67 indexing. We therefore aimed to determine associations of the Ki67...
SURGICAL RELEASE FOR TENNIS ELBOW-A CASE SERIES AT VIMS, BELLARY
OBJECTIVE: To assess the outcome of open release in the management of resistant tennis elbows, based on patient satisfaction. METHODS: This was an observational retrospective case series of 25 consecutive patients that u...
AQUIRED IMMUNO DEFICIENCY SYNDROME AND ITS OPHTHALMIC MANIFESTATIONS. SHORT REVIEW ARTICLE.
Rising trend of HIV seropositivity in TB patients in India and involvement of multi organ system and multiple opportunistic infections in AIDS is quite worrying1-3. India is emerging globally as a country with the larges...
A REVIEW ON ROLE OF PERIDURAL FIBROSIS AND ITS DIAGNOSIS
FBSS is a challenging clinical entity with significant impact on the individual and society. To better prevent and manage this condition, knowledge of the factors contributing to its development is necessary. While resea...
NUTRITIONAL PROBLEM IN MANDSAUR (M.P.)
Malnourishment and starvation has taken its toll twice on Subash Bheel (a resident of Hingua village, in Badwani district in Madhya Pradesh) who lost 2 of his children (Rakesh and Gaurav) in the last two months. Subhash...