Microbiological Profile of Bronchoalveolar Lavage in Patients with Nosocomial Pneumonia in Intensive Care Unit
Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 7
Abstract
Introduction: Intensive Care Units (ICU) are a major threat to nosocomial pneumonias. It is defined as manifestation of infection after 48 hours of hospital admission which can be also attributed to any procedures done to the patient. As resistance to these microorganisms are on the rise in ICU, it is indeed necessary to find out microorganisms and their resistance patterns in ICUs of each institute. Aim: To find out the most common microorganism with pulmonary involvement in the ICU setup and to determine the sensitivity patterns of microorganisms to the antibiotics by doing Bronchoalveolar Lavage (BAL). Materials and Methods: A retrospective study was done at a tertiary care centre in Chennai, India, over a period of one year (from January 2017 to December 2017). The study included microbiological reports collected from 92 BAL samples with a diagnosis of pneumonia after 48 hours of ICU admission. Results: The most common organism isolated was Acinetobacter {36/92 (39%)} followed by Klebsiella Pneumonia {28/92 (31%)} and Pseudomonas {12/92 (13%)}. Acinetobacter was mainly isolated from intubated patients with a sensitivity of 28% to the common broad spectrum antibiotics and 100% to Colistin. While 40% Klebsiella pneumoniae was sensitive to only Colistin and Polymixin, all the Pseudomonas isolates were sensitive to the common broad spectrum antibiotics like Piperacillin-Tazobactum, Amikacin, Cefperazone-Sulbactum. Conclusion: As per the present study Acinetobacter was the most common organism isolated from ventilator associated pneumonia patients with a high percentage of resistant strains followed by Klebsiella and Pseudomonas. Although, all the microorganisms were sensitive to high level antibiotics only a few were sensitive to the common broad spectrum antibiotics.
Authors and Affiliations
Kalyani Sri Koneru, Priya Joy, V Gangadharan, Ashok Kumar, Sathish Kumar
Keywords
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- EP ID EP523963
- DOI 10.7860/JCDR/2018/36708.11794
- Views 63
- Downloads 0
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