Microbiological study of methicillin-resistant Staphylococcus aureus isolated from wound samples at a tertiary care hospital, Central India
Journal Title: Asian Pacific Journal of Health Sciences - Year 2018, Vol 5, Issue 1
Abstract
Background: Staphylococcus aureus continues to be a dangerous pathogen for both community-acquired as well as hospital-associated infections. S. aureus resistant to methicillin were reported soon after its introduction in October 1960. Methicillin-resistant S. aureus (MRSA) is now endemic in India. MRSA has recently emerged as a major nosocomial pathogen worldwide with a significant morbidity and mortality. Materials and Methods: This study was thus undertaken to characterize MRSA isolates, isolated from wound samples from a tertiary care teaching hospital in Central India and to also probe antibiotic susceptibility of its clinical isolates. Results: About 120 MRSA isolates from various clinical samples such as pus swabs and aspirates, blood, urine, sputum, and endotracheal tube aspirates were collected and processed in the laboratory for various tests. Of 120 isolates subjected to gelatin liquefaction test with appropriate controls, 104 were found to be positive while 16 were tested negative. Majority of the hospital-associated MRSA (HA-MRSA) patients were in the age group of >50 years of age 42 (35%) followed by the 41–50 years of age group 26 (21.7%). The age in the HA-MRSA group varied from 18 to 75 years with mean age of 41.2 ± 22.29. Majority of the HA-MRSA infections presented as cellulitis (41.9%), followed by abscess (28.9%) and post-operative wound discharge (23.8%), whereas most of the community-associated-MRSA infections presented as abscesses (83.5%), followed by furuncle (9.6%), and cellulitis and carbuncle (2.8% each). Among 120 isolates subjected to alkaline phosphatase test, 114 were found to be phosphatase positive while 6 being phosphatase negative. Conclusion: Our study is a preamble to enable epidemiologists to understand the nature of MRSA isolates in this part of India. There is a need to study epidemiology of such infections. Robust antimicrobial stewardship and strengthened infection control measures are required to prevent spread and reduce emergence of resistance.
Authors and Affiliations
Prashant Peshattiwar
Keywords
Related Articles
- EP ID EP519618
- DOI 10.21276/apjhs.2018.5.1.25
- Views 223
- Downloads 0
Glomus Tumor of Digit: A Case Report
Glomus tumors are one of the rare benign tumors accounting for <2% of all the soft tissue tumors in the body with a female propensity and more commonly seen in digits. We report a case of glomus tumor in a 34-year-old fe...
Riedel’s thyroiditis presenting as large retropharyngeal goiter - A rare case
The thyroid gland lies in the anterior triangle of the neck in close approximation to the larynx and the trachea. The extension of an enlarged thyroid gland outside the normal confines of the thyroid bed is well known. A...
Community attitudes towards mental illness
This article reviews the literature on the community attitudes and suggestions are made for future research and lessons to be learnt from the experience in Zambia. Stigma, discrimination and social exclusion have been id...
A Comparative Study of Racedrotril and Single Dose Octreotide in Acute Diarrhoea
To assess the efficacy of single dose of octreotide and compare it with another antisecretory agent racecadotril in the management of acute infective diarrhoea. A Randomised control study was carried out on the acute dia...
Buccal fat pad graft in oral and maxillofacial surgery-A review
Buccal fat pad is much underutilized graft in oral and maxillofacial surgeries. Although, it has been recognized in early seventeenth century, but its use in different conditions as a graft was popularized after mid eigh...