Microfluidics for antibody-independent separation of circulating tumor cells

Journal Title: Journal of Medical and Scientific Research - Year 2018, Vol 6, Issue 1

Abstract

Separation of circulating tumor cells (CTC) from the blood without using antibodies is a key challenge in the diagnosis of cancer. This article has reviewed few antibody-independent techniques governed by cell size on microfluidics platform. Microdevices employing micro-pore filters, dielectrophoresis, acoustophoresis and inertia that is popular in various research labs are studied in detail from the literature and discussed shortly. The inertia based technique in spiral microchannel seems to be more promising towards the development of future point-of-care (POC) microdevices for CTCs separation.

Authors and Affiliations

Vijay Duryodhan, Shiv Govind Singh

Keywords

Related Articles

Arthroscopic ACL reconstruction with aperture interference fixation: Graft comparison, BPTB versus hamstring tendon- Cohort study with two year follow-up

Purpose: To compare the results of a single surgeon, arthroscopically assisted Anterior cruciate ligament (ACL) reconstruction with the Bone-patellar tendon-bone (BPTB) and the hamstring tendons grafts using aperture scr...

Point of view on measurement uncertainty in terms of quality management

All types of measurements have some inaccuracy due to bias and imprecision. Quality control (QC) checks are meant to watch and establish precision of the test results. When we speak of a measurement, we often want to kno...

Stent thrombosis: Prevention and management

Stent thrombosis (ST) is a persistent and important clinical problem. Stent thrombosis has been defined and classified by the Academic Research Consortium (ARC). We have reviewed the data available on the incidence of ST...

Anesthesia for bariatric surgery- our experience

Bariatric surgery is becoming a popular choice for the treatment of morbid obesity. Laproscopy-sleeve gastrectomy is one of the most effective methods for treating patients with morbid obesity. Anaesthesiologist has a ve...

Bipolar arthroplasty for unstable Intertrochanteric fractures of femur

Intertrochanteric (IT) fractures of femur are common in elderly people with osteoporotic bones and often the result of minor domestic falls. Osteoporosis coupled with a tendency to fall is responsible for high incidence...

Download PDF file
  • EP ID EP590744
  • DOI 10.17727/JMSR.2017/5-12
  • Views 97
  • Downloads 0

How To Cite

Vijay Duryodhan, Shiv Govind Singh (2018). Microfluidics for antibody-independent separation of circulating tumor cells. Journal of Medical and Scientific Research, 6(1), 61-65. https://europub.co.uk/articles/-A-590744