MICROSPHERE: A REVIEW
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 7
Abstract
Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers having a particle size ranging from 1-1000 μm. The range of Techniques for the preparation of microspheres offers a Variety of opportunities to control aspects of drug administration and enhance the therapeutic efficacy of a given drug. There are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release fashion. One such approach is using microspheres as carriers for drugs also known as microparticles. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs. In future by combining various other strategies, microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, gene & genetic materials, safe, targeted and effective in vivo delivery and supplements as miniature versions of diseased organ and tissues in the body.
Authors and Affiliations
Vijay Yadav| M Pharm., Pharmaceutics, Jaipur College of Pharmacy, Jaipur, Rajasthan, H. M. Varshney*| Faculty of Pharmaceutics, Jaipur College of Pharmacy, Jaipur, Rajasthan
Keywords
Related Articles
- EP ID EP1428
- DOI -
- Views 509
- Downloads 30
A non-traditional therapeutic strategy in management of fulminant hepatic failure: histopathological and immunohistochemistry study
The present study was undertaken to evaluate the crucial role of hepatocytes transplantation in experimental model of D-galactosamine induced fulminating hepatic failure (FHF) in rat. Hepatocytes were isolated and grown...
Possible Study of Drug-Drug Interactions between Lisinopril and Gliclazide in Experimental Animals
The most often problem in type II diabetic patients coexists with hypertension, the incidence of hypertension among diabetic patients is high. In this case, use a combination of medicine unavoidable (Polypharmacy). In su...
STUDY ON CONSERVATIVE TREATMENT IN EARLY OTHEMATOMA IN A TERTIARY CARE HOSPITAL IN EASTERN INDIA
OBJECTIVES: To evaluate a conservative treatment strategy in othematoma. METHODS: Study was done with 31 patients with othematoma. These patients were treated in “outpatient department” with aspiration of hemarregic flui...
Screening of solvent extracts of catharanthus roseus l. for isolation of anti-inflammatory compound
Catharanthus roseus (L.) which is an important medicinal plant of the family Apocynaceae is used to treat many of the fatal diseases. C. roseus also possess good antioxidant potential. Catharanthus roseus, is a potent me...
EXTRACTION AND ISOLATION OF α -AMYRIN ACETATE FROM THE FRUITS OF FICUS RACEMOSA
Ficus racemosa Linn belongs to the family Moraceae is popular in indigenous system of medicine like ayurveda, siddha, unani and homoeopathy. It has been known to posses diverse pharmacological activities. In the traditio...