Microsurgical treatment of severe aneurysmal subarachnoid hemorrhage: an analysis of 14 cases
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 4
Abstract
"<b>Objective</b> To analyze the therapeutic effect of microsurgery on patients with severe aneurysmal subarachnoid hemorrhage (SaSAH). <b>Methods</b> A retrospective analysis was conducted on 14 SaSAH patients admitted to Beijing Chao-Yang Hospital, Capital Medical University from December 2017 to November 2019. General information, Hunt Hess grading, Glasgow Coma Scale (GCS), time of rebleeding, surgery time, examination method, aneurysm size, prognosis, and postoperative follow-up were collected. <b>Results</b> A total of 14 patients with SaSAH were enrolled, including 5 males and 9 females, 8 patients with Hunt-Hess grade Ⅳ and 6 with grade Ⅴ. Seven cases experienced rebleeding after admission, with an average time between the onset of symptoms and rebleeding being 11.21 hours. Intracranial aneurysm rupture was confirmed by computed tomography angiography (CTA) or digital subtraction angiography (DSA) before operation in 13 cases. All 14 patients underwent microsurgical aneurysm clipping after definite diagnosis. There were 5 cases of transtentorial herniation and 3 cases of subfalcine herniation. Bone flaps were removed during surgery for all patients with cerebral herniation. In 14 cases, Glasgow prognostic score (GOS) was 4 in 2 cases, 3 in 3 cases, 2 in 7 cases, and 1 in 2 case at 6 months follow-up. <b>Conclusion</b> Treating SaSAH responsible aneurysms within 24 hours is an important principle for preventing intracranial rebleeding, reducing mortality, and improving prognosis. Microsurgery remains an important method for treating SaSAH, especially for patients with intracranial hematoma and progressive intracranial hypertension."
Authors and Affiliations
GUO Peng, SONG Yinglun, LI Xiong, TAN Ke, WANG Yu, LI Tao, PENG Yutao, ZHANG Haoyu, DONG Le, WU Wenqian, LI Jinping
Keywords
Related Articles
- EP ID EP734612
- DOI 10.13429/j.cnki.cjcr.2024.04.015
- Views 49
- Downloads 0
Protective effect of esketamine on hepatic ischemia-reperfusion injury
Esketamine, as a perioperative sedative and analgesic drug, has been widely used in Europe and America. However, the protective effect of esketamine on the liver during the perioperative period is still in the applicated...
Neuronavigation-guided percutaneous balloon compression for treatment of primary trigeminal neuralgia in elderly patients
Objective：To explore the clinical application effect of percutaneous balloon compression (PBC) under neuronavigation guidance for the precise treatment of trigeminal neuralgia in elderly patients. Methods：A retrospecti...
Clinical significance and research progress of microsatellite instability in gastric cancer
The occurrence and development of gastric cancer (GC) is determined by many factors. In recent years, the development of molecular biology has provided new ideas for the diagnosis and treatment of GC. Microsatellite inst...
Research progress on the clinical application of PCSK9 inhibitors in coronary heart disease
Coronary heart disease (CHD) is currently an important cause of mortality among residents in China and worldwide. The incidence of CHD in China is increasing annually. Among the various factors leading to the occurrence...
Claudin18.2： an emerging target for the treatment of gastric cancer
Gastric cancer is a malignant tumor that seriously endangers human health. Claudin18.2 (CLDN18.2) is a transmembrane protein and a main component of tight junctions that plays an important role in maintaining barrier fun...