Microwave-assisted multicomponent reaction for the synthesis of 2-amino-4H-chromene derivatives using ilmenite (FeTiO3) as a magnetic catalyst under solvent-free conditions
Journal Title: Asian Journal of Green Chemistry - Year 2017, Vol 1, Issue 1
Abstract
A green and highly efficient method has been developed for the synthesis of 2-amino-4H-chromene derivatives in the presence of FeTiO3 as magnetic catalyst via one-pot three-component condensation reaction of aromatic aldehydes, malononitrile and α- or β-naphthol without solvent under microwave irradiation. Mild reaction conditions, short reaction times, simple work-up, use of an economically convenient catalyst, and excellent product yields are the advantageous features of this method. The catalyst can be easily recovered by a simple magnetic separation and can be recycled six times with no significant loss of catalytic activity.
Authors and Affiliations
Ali Ramazani, Saeid Taghavi Fardood, Behrooz Ebadzadeh, Pegah Azimzadeh Asiabi, Yousef Bigdeli Fard
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