MIDAZOLAM AS AN ADJUVANT TO BUPIVACAINE IN SUPRACLAVICULAR APPROACH OF BRACHIAL PLEXUS BLOCK
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 61
Abstract
BACKGROUND Brachial plexus block in supraclavicular approach is a very good postoperative analgesia. Midazolam, a water-soluble benzodiazepine has been used by various routes to prolong analgesia. The analgesic efficacy of midazolam with bupivacaine in brachial plexus block produces significantly faster onset of sensory and motor blockade and prolongs the duration of sensory and motor block and duration of analgesia. The aim of this study is to compare the effectiveness of addition of midazolam as an adjuvant to bupivacaine in supraclavicular approach of brachial plexus block in upper limb surgery. MATERIALS AND METHODS 60 patients were recruited to two groups. Group B received 30 mL of 0.375% Bupivacaine and Group BM received 30 mL of 0.375% Bupivacaine and 50 mcg/kg of Midazolam. RESULTS On addition of midazolam to bupivacaine, there was significant difference in onset of sensory and motor block compared to bupivacaine. There is prolongation in duration of analgesia, duration of sensory and motor blockade. There is no significant difference in haemodynamics and no side effects like hypotension, bradycardia or respiratory depression. CONCLUSION The addition of midazolam to LA solution in supraclavicular approach to brachial plexus block produces significantly faster onset of sensory and motor blockade and prolongs the duration of sensory and motor block and duration of analgesia.
Authors and Affiliations
Sakuntala Muniyandi, Bala Subramani Murugesan, Chithra Devi Ramakrishnan
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