Minimizing Bioavailability of Fluoride through Addition of Calcium-magnesium Citrate or a Calcium and Magnesium-containing Vegetable to the Diets of Growing Rats
Journal Title: International Journal of Biochemistry Research & Review - Year 2016, Vol 10, Issue 2
Abstract
Introduction: Fluorosis is a public health problem in Ethiopia. Fluoride absorption may be decreased by dietary divalent cations which form insoluble complexes with the fluoride ion. Aim: This study aimed to assess the effect of dietary calcium-magnesium citrate or Moringa stenopetala dry leaf on apparent absorption of fluoride in animals. Samples: Animals (14 weeks) were on fluoridated/non-fluoridated water and calcium and magnesium supplemented diet. Study Design: Rats received fluoridated or non-fluoridated (control) water (10 mg/L) with or with out calcium magnesium citrate (0.5 mg) or moringa stenopetala dry leaf powder(0.1 g) blended with daily ration. Place and Duration of Study: Department of food science and nutrition research, Ethiopian Public Health Institute, 2014. Methods: Twelve female Wistar rats of similar age (14 weeks) and weight (186.7±5.4 g) were placed in metabolic cages for 42 consecutive days and given one of 4 treatments: corn-soya blend (CSB control); CSB and fluoridated water (10 mg/L F); CSB, fluoridated water (10mg F/L) and calcium-magnesium citrate (0.5 mg); CSB, fluoridated water (10 mgF/L) and Moringa stenopetala (0.1 g). Urine and faeces were collected weekly. Results: Supplementation of calcium-magnesium or Moringa stenopetala leaf significantly (p < 0.05) reduced urinary fluoride and increased fecal fluoride level, indicating less absorption of fluoride. Conclusion: This study provides evidence for a dietary approach in reducing fluorosis.
Authors and Affiliations
Aweke Kebede, Nigussie Retta, Cherinet Abuye, Susan J. Whiting, Melkitu Kassaw, Tesfaye Zeru, Meseret Woldeyohannes, Marian K. Malde
Keywords
Related Articles
- EP ID EP351105
- DOI 10.9734/IJBCRR/2016/23693
- Views 125
- Downloads 0
Coffee and Caffeine Consumption in Reproductive Functions of Adult Wistar Rats
Coffee from Coffea arabica is a popular beverage consumed worldwide. Its effect on health has been a global puzzle. In this study, the effect of coffee and caffeine consumption on some reproductive structures and functio...
Genetic Diversity and Relationships between and within Kiwifruit (Actinidia) Wild Species and Cultivated Varieties Using SRAP Markers
Introduction: Kiwifruit (Actinidia) is one of the most important fruits in the world. Genetic diversity may provide the raw materials for programmers of plant breeding and crop improvement. Materials and Methods: The aim...
Effects of Opium Addiction on Some Biochemical Parameters in Diabetic Rats
These days, opium consumption has increased among people. Opium latex contains approximately 12% of the analgesic alkaloid morphine, which is processed, chemically to produce heroin and other synthetic opiates for medici...
Effect of Drying Methods and Storage Conditions on Nutritional Value and Sensory Properties of Dehydrated Tomato Powder (Lycopersicon esculentum)
The effects of two drying methods, (oven drying and sun drying) of tomatoes and storage conditions of the products were studied to assess their effects on chemical, nutritional quality and sensory properties. Eleven kilo...
Chelation Potential of Aqueous Leaf Extracts of Vernonia amygdalina and Phyllanthus amarus on Kidney Functions in Lead-intoxicated Albino Wistar Rats
The aim of the study was to investigate the chelation potential of aqueous leaf extracts of Vernonia amygdalina and Phyllanthus amarus in albino wistar rats intoxicated with lead using kidney function markers as indicato...