MODERN UNDERSTANDINGS OF THE ORIGINS AND MANAGEMENT OF ONGOING PURULENT EAR INFECTIONS (CHRONIC SUPPURATIVE OTITIS MEDIA)
Journal Title: International scientific journal Science and Innovation - Year 2024, Vol 3, Issue 9
Abstract
Otitis media (OM) is basically a kind of swelling in the middle ear that is usually linked to an infection. Even with proper treatment, acute OM (AOM) might, unfortunately, turn into chronic suppurative OM (CSOM), which often involves a tear in the ear drum and some nasty discharge. This fluid tends to block the tiny bones in the middle ear from sending sound waves from the ear drum to the oval window of your inner ear correctly, which more or less results in conductive hearing loss. Plus, it is pretty common for the inflammatory substances created during CSOM to actually seep into your inner ear through something called the round window. This can, more or less, lead to the destruction of hair cells in the cochlea, resulting in sensorineural hearing loss. Pseudomonas aeruginosa and Staphylococcus aureus are typically the main culprits that often cause CSOM. Although, as a matter of fact, the pathogenesis of AOM is thoroughly examined, there is very limited research available regarding CSOM. With antibiotic resistance emerging (in some respects) alongside the ototoxicity of antibiotics and potential surgical risks, there is an urgent need to create effective treatment strategies against CSOM. This means it is crucial to understand how host immunity works in cases of CSOM and how these bacteria dodge such potent immune responses. Figuring out the molecular pathways leading to CSOM will aid in developing new treatments for the disease and might be able to prevent hearing loss.
Authors and Affiliations
Rajabov A. Kh. , Amanov Sh. E. , Urinbaeva N. M.
Keywords
Related Articles
- EP ID EP748031
- DOI 10.5281/zenodo.13879505
- Views 53
- Downloads 0
DETERMINATION OF PREDISPOSITION TO DISEASES OF THE PERITONEUM AFTER ABDOMINAL SURGERY IN CHILDREN
The authors studied one of the pathogenetic factors of adhesive disease in 53 sick children, predisposition to adhesive diseases and measures to prevent premature formation of adhesions. Predisposition to adhesive diseas...
IMPLEMENTING HANDS-ON ARMV8 INSTRUCTIONAL ACTIVITIES IN COMPUTER ARCHITECTURE EDUCATION: A CASE STUDY
In today’s rapidly evolving technological landscape, computer architecture education plays a pivotal role in shaping the next generation of engineers and computer scientists. As ARM-based systems gain prominence across v...
USING MAGAZINES FOR DEVELOPING READING SKILLS
Using magazine as a reading material in the classroom can bring many benefits to students' learning process. It can make the learning experience more interesting and engaging, provide a variety of reading materials, expo...
ASSESSMENT OF TRANSPORT AND OPERATIONAL INDICATORS OF MANNON UYGUR STREET IN TASHKENT
This article describes the transport-operational indicators of the city streets, and the transport-operational indicators include the following: Roughness of the surface course of the pavement; Durability of road pave...
THE CONCEPT OF PERSONAL COMPETENCE AND CREATIVITY OF A MUSIC TEACHER IN THE EDUCATIONAL SYSTEM
The article discusses the different stages of preschool age and the development of musical abilities in children. Additionally, the article mentions various sources related to the development and education of music in Uz...