Modulatory roles of ergothioneine on heat shock protein-70, tumour necrosis factor-alpha, and rectal temperatures of Arabian stallions following race of 2000 m in a hot-dry environment
Journal Title: Iranian Journal of Veterinary Science and Technology (IJVST) - Year 2022, Vol 14, Issue 4
Abstract
Experiments were performed to determine the effect of ergothioneine on rectal temperature and the serum concentrations of heat shock protein-70 (HSP-70) and tumor necrosis factor-α (TNF-α) in stallions following a race of 2000 m in a hot-dry environment. Eighteen stallions weighing approximately 400 kg each were used for the experiment. They were divided into three groups of six stallions each. Group I (EEX) was the experimental group that was administered ergothioneine (0.5 mg/kg per os), while group II (EEC) did not receive ergothioneine before exercise. The third group (EEN) was neither administered ergothioneine nor exercised. The dry-bulb temperature and the relative humidity of the experiment were determined for six days and on the day of the experiment. The temperature-humidity index was also calculated. Rectal temperature, serum HSP-70, and TNF-α concentrations of all horses were measured before commencement, immediately after, and 2 h after the exercise. The dry-bulb temperature and relative humidity which showed diurnal fluctuations increased significantly (p < 0.05) between 06.00 h and 12.00 h (22.6 ± 1.23 and 38.6 ± 6.5, respectively). Serum TNF-α and HSP-70 levels of the stallions in the EEX group were higher than the values obtained in the EEC and EEN groups (p < 0.05). The values of rectal temperature obtained were lower (p < 0.05) in the EEX group than in the other groups. Therefore, it could be concluded that ergothioneine modulated rectal temperature, as well as TNF-α and HSP-70 concentrations in the stallions, and might be beneficial to horses during exercise.
Authors and Affiliations
Adakole Adah,Joseph Ayo,Peter Rekwot,Tagang Aluwong,Deborah Adah,
Modulatory roles of ergothioneine on heat shock protein-70, tumour necrosis factor-alpha, and rectal temperatures of Arabian stallions following race of 2000 m in a hot-dry environment
Experiments were performed to determine the effect of ergothioneine on rectal temperature and the serum concentrations of heat shock protein-70 (HSP-70) and tumor necrosis factor-α (TNF-α) in stallions following a race...
Causes for Carcass Condemnations of Slaughtered Poultry in the Industrial Slaughterhouse of Namin, Ardabil Province, Iran
Poultry meat production worldwide has continued to expand over the last two decades. In this regard, hygienic meat inspection and monitoring of diseases at slaughter lines have been recognized as essential for assessing...
Molecular epidemiology of Campylobacter Fetus in aborted fetuses of Baluchi sheep in Sistan region
Campylobacter is one of the main bacterial causes of ewe abortion throughout the world. Campylobacter infections are now considered as zoonoses. The objective of this study was an investigation of Campylobacter fetus pre...
A survey on Feline Leukemia virus infection in cats of Ahvaz district, Iran: Seroprevalence and risk factors
The purpose of the present survey was to determine the seroprevalence rate of FeLV in cats in Ahvaz district, South-West of Iran, as well as, risk factors such as age, gender, breed, life style and clinical findings were...
Assessment of some inflammatory cytokines and immunologic factors in dairy cows with subclinical ketosis
Altered cytokine profile and weakened immunity along with clinical or subclinical ketosis (SCK) are among the remarkable challenges around parturition. Therefore, the present study aimed to compare some inflammatory cyto...