MOLECULAR COMPLEXES OF GERMANIUM TETRACHLORIDE WITH NIACIN, NICOTINIC AMIDE, ISONICOTINIC HYDRAZIDE AND THEIR PHARMACOLOGICAL ACTIONS
Journal Title: Вісник Одеського національного університету. Хімія - Year 2016, Vol 21, Issue 2
Abstract
Synthesized in different organic solvents and characterized by elemental and X-ray diffraction, thermogravimetry, IR spectroscopy molecular complexes of germanium tetrachloride with niacin, nicotinic amide and isonicotinic hydrazide. Determined that in obtained compounds the coordination of the ligand is due to the unshared electron pair on the nitrogen atom of the heterocycle. Proposed structure of the complexes. Showed their high antihypoxic, hepatoprotective, antioxidant and membrane-stabilizing activity of the synthesized compounds.
Authors and Affiliations
I. I. Seifullina, E. E. Martsinko, N. M. Khristova, E. A. Chebanenko
Keywords
Related Articles
- EP ID EP337054
- DOI 10.18524/2304-0947.2016.2(58).74777
- Views 93
- Downloads 0
ADSORPTION OF IONS LANTAN ON KAOLIN
The results of studies of the adsorption of lanthanum ions from aqueous solutions of kaolin are presented. It has been shown that kaolin is a fairly effective adsorbent of lanthanum ions from aqueous solutions with diffe...
THE RESEARCH OF PROCESS OF LEACHING OF COALCONCENTRATING DUMPS IN POTENTIOSTATIC MODE
Determination of influence of potential value of discharge on process of leaching of dump of technogenic origin by mineral solution was the purpose of the research. Object of the research was dump of technogenic origin w...
INTERACTION OF THE LANTHANA, YTTRIA WITH NEODYMIA AT TEMPERATURE 1600 °C
First, the phase equilibria in the ternary La2О3–Y2O3–Nd2О3 system at 1600 °C were studied by X–ray diffraction and petrography in the overall concentration range. The samples of different compositions have been prepared...
MOLECULAR COMPLEXES OF GERMANIUM TETRACHLORIDE WITH NIACIN, NICOTINIC AMIDE, ISONICOTINIC HYDRAZIDE AND THEIR PHARMACOLOGICAL ACTIONS
Synthesized in different organic solvents and characterized by elemental and X-ray diffraction, thermogravimetry, IR spectroscopy molecular complexes of germanium tetrachloride with niacin, nicotinic amide and isonicotin...
THE IMPACT OF CONFORMATIONAL CHANGES IN ALBUMIN MOLECULE (BSA) ON THE SPECTRAL PROPERTIES OF SQUARAINE AND DICYANOMETHYLENE SQUARAINE DYES
The work was to develop a highly sensitive, fluorescence based method to monitor conformational changes in proteins. With this aim, the influence of unfolding of bovine serum albumin (BSA) molecules on the spectral prope...