Molecular Detection of HCV and HBV in HIV positive patients in Chaharmahal and Bakhtiari Province
Journal Title: Khoon - Year 2019, Vol 15, Issue 4
Abstract
Molecular Detection of HCV and HBV in HIV positive patients in Chaharmahal and Bakhtiari Province Taheri F.1,2, Tajbakhsh E.3, Heidari Soureshjani E.1,2 1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran 2Shahrekord Blood Transfusion Center, Shahrekord, Iran 3School of Basic Sciences, Islamic Azad University of Shahrekord Branch, Shahrekord, Iran Abstract Background and Objectives Viral hepatitis B and C are considered to be a medical problem for people with HIV infection. The importance of these infections is in the shared route of their transmission, and liver disease as a result of infection with HCV, HBV and HIV infection that can lead to death. Materials and Methods In this cross-sectional descriptive study, a total of 31 serum samples were prepared from patients referring to the Behavioral Diseases Counseling Center in Chaharmahal and Bakhtiari province who were diagnosed with HIV infection by Western blotting method; their consent was taken. The coinfection with HBV and HCV was investigated by PCR method. Data were analyzed by fisher exact test and prism7 software. Results The results of this study on serum samples of HIV-infected people showed the prevalence of HCV/HBV coinfection in HIV-positive individuals to be %3.22, the prevalence of HBV infection in HIV-positive individuals %4.45, and the prevalence of HCV infection in HIV infected ones %22.5. Conclusions According to the common routes of transmission of HCV, HBV, and HIV viruses, it is essential that all people who are HIV-positive or HIV-infected be screened for hepatitis B and C viruses by highly sensitive diagnostic methods. Key words: Coinfection, Hepatitis B, Hepatitis C, HIV, Molecular Diagnostics Received: 12 Mar 2018 Accepted: 25 Sep 2018 Correspondence: Tajbakhsh E., PhD of Microbiology. Associate Professor of School of Basic Sciences, Islamic Azad University of Shahrekord Branch. P.O.Box: 166, Shahrekord, Iran. Tel: (+9838) 33335457; Fax: (+9838) 33331482 E-mail: ee_tajbakhsh@yahoo.com
Authors and Affiliations
F. Taheri, E. Tajbakhsh
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