Molecular Imaging of Bacterial Infections in vivo: The Discrimination between Infection and Inflammation
Journal Title: Informatics - Year 2014, Vol 1, Issue 1
Abstract
Molecular imaging by definition is the visualization of molecular and cellular processes within a given system. The modalities and reagents described here represent a diverse array spanning both pre-clinical and clinical applications. Innovations in probe design and technologies would greatly benefit therapeutic outcomes by enhancing diagnostic accuracy and assessment of acute therapy. Opportunistic pathogens continue to pose a worldwide threat, despite advancements in treatment strategies, which highlights the continued need for improved diagnostics. In this review, we present a summary of the current clinical protocol for the imaging of a suspected infection, methods currently in development to optimize this imaging process, and finally, insight into endocarditis as a model of infectious disease in immediate need of improved diagnostic methods.
Authors and Affiliations
Heather Eggleston and Peter Panizzi
Keywords
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- EP ID EP44033
- DOI https://doi.org/10.3390/informatics1010072
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