MONITORING OF THYROID HORMONES LEVELS IN DIABETIC MELLITUS TYPE 2 PATIENTS CONTROLLED AND UNCONTROLLED IN SANA’A, YEMEN
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2017, Vol 4, Issue 4
Abstract
Background: Diabetes mellitus (DM) is a common endocrine metabolic disorder and variety of thyroid abnormalities may coexist and interact with DM that appears to influence thyroid function. Objective: Therefore, the study aimed to monitor the thyroid hormones levels in DM type 2 patients controlled and uncontrolled in Sana’a, Yemen. Methods: The study included 150 subjects from major public hospitals in Sana'a city, Yemen. 50 were diagnosed with DM type 2 controlled as group I and 50 were diagnosed with DM type 2 uncontrolled as group II. 50 were healthy volunteers as control group. The biochemical parameters namely Fasting Blood Sugar (FBG) and Glycelated Hemoglobin (HBA1c) were assayed in three groups. On the other hand, thyroid hormones levels namely thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4) were monitored in the same groups. Data obtained were analyzed using suitable statistical tools. Results: The levels of thyroid hormones in DM type 2 patients controlled and uncontrolled were recorded. The mean of TSH, FT3, and FT4 levels were recorded in three groups. The results were (1.83± 0.791 mU/L , 3.0 ±2.2 mU/L, 1.83 ±0.85 mU/L); (3.47± 0.78 Pg/mL , 2.9 ± 0.74 Pg/mL,4.1± 0 .71 Pg/mL) ; (1.1 ± 0 .212 ng/dl, 1.01 ± 0.33 ng/dl , 1.2 ± 0.14 ng/dl), respectively. The results were observed that different significant (p < 0.05) in in TSH and Free T3 levels between groups I and II. While different significant (p > 0.05) in FreeT3 and Free T4 between group I and III. Also, the different significant in three hormones levels between group II and III. On the other hand , the present study showed 20 % of patients had thyroid dysfunction. 17 % of hypothyroidism and 3% of hyperthyroidism. However, 2% of hypothyroid in controlled patients and 15 % of hypothyroid in uncontrolled patients, while 2% of hyperthyroidism was found in controlled patients and 1 % of hyperthyroidism was recorded in uncontrolled patients. Conclusion: The study outcome concluded that the thyroid dysfunction may progressive in DM type 2 patients uncontrolled as complication.
Authors and Affiliations
Mohammed Amood AL-Kamarany
Keywords
Related Articles
- EP ID EP628940
- DOI -
- Views 164
- Downloads 0
SERO-PREVALENCE OF HEPATITIS C VIRUS INFECTIONS AMONG BLOOD DONORS AND CLINICAL VISITORS IN AMRAN GOVERNORATE,YEMEN
Hepatitis C virus is identified as a member of the RNA Flaviviridae that can cause acute and chronic infections in human. So, the present study was conducted in Amran general hospital, Amran city, Yemen, eight hundred (8...
OUTCOME OF AUTOGENOUS VERSUS ALLOPLASTIC GRAFTS (MEDPORE) FOR RECONSTRUCTIVE AUGMENTATION RHINOPLASTY
Background: Many nasal deformities are requiring correction by augmentation rhinoplasty. Autologous and alloplastic graft materials have been used for nasal dorsal reconstruction. Objectives: This study was designed to c...
ANALYSIS FOR EPHEDRINE ALKALOID UTILIZING ISOCRATIC HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
A method to assay ephedrine hemihydrate (ephedrine alkaloid), which has various biological activities, is presented using isocratic high performance liquid chromatography (HPLC). Elution of the analyte is detected with u...
CONTRIBUTION STUDY TO THE CHEMICAL COMPOSITION OF THE VOLATILE OIL IN PELARGONIUM GRAVEOLENS, AN AROMATIC PLANT WIDELY SPREAD IN DAMASCUS-SYRIA
Many medicinal plants are present in Damascus, which are widely used in traditional medicine, and in the food industry as flavor and preservative. The aim of this Study focused on the volatile oil in this Plant, Pelargon...
DOES PUMPKIN AFFECT GLYCEMIC CONTROL IN DIABETIC PATIENT. CASE REPORT AND LITERATURE REVIEW
Pumpkin was reported to have hypoglycemic effect. It has been used in asia as traditional treatment for diabetes mellitus. Here we report 12 year old Saudi who is diagnosed as diabetes mellitus type 1. The pumpkin was fe...