Montelukast versus inhaled mometasone for treatment of otitis media with effusion in children: A randomized controlled trial
Journal Title: Electronic Physician - Year 2017, Vol 9, Issue 7
Abstract
BACKGROUND: Otitis media is one of the most common infections among children and is a complication in about 30% of common colds. The most common complication of acute otitis media is otitis media with effusion. Some studies have reported the effects of montelukast and mometasone nasal spray in treatment of otitis media with effusion. However, current information is inadequate in this issue. OBJECTIVE: To compare the effectiveness of montelukast and mometasone nasal spray in treatment of otitis media with effusion in children attending Koodakan hospital in Bandar Abbas, Iran. METHODS: This randomized controlled trial was done on 2- to 6-year-old children attending Koodakan Hospital in Bandar Abbas, southern Iran, in 2014. Patients were divided into three groups of montelukast, mometasone, and control group. Audiometry was done for all patients at baseline and four weeks after treatment. Patients were compared for treatment results. Data were analyzed using SPSS 21.0 software. RESULTS: A total of 143 children were included in the study. Mean age of the participants were 44.64 ± 18.03 months. There was no significant difference in treatment results in different treatment groups (p>0.05). CONCLUSION: Mometasone and montelukast are not effective and not recommended in treatment of otitis media with effusion in children. More studies are needed in this regard. TRIAL REGISTRATION: This study is registered at ClinicalTrials.gov with ClinicalTrials.gov Identifier: NCT02541760. FUNDING: The authors received financial support for this research from Hormozgan University of Medical Sciences
Authors and Affiliations
Mohammad Bagher Rahmati, Fatemeh Safdarian, Babak Shiroui, Shahram Zare, Naser Sadeghi
Keywords
Related Articles
- EP ID EP323645
- DOI 10.19082/4890
- Views 61
- Downloads 0
Levels of cytokines in the aqueous humor of eyes with primary open angle glaucoma, pseudoexfoliation glaucoma and cataract
OBJECTIVE: The focus of this study aimed at measuring multiple inflammatory cytokines levels in the aqueous humor of patients with primary open angle glaucoma (POAG), pseudoexfoliation glaucoma (PEXG) and senile cataract...
Seasonal Distribution of Fungi in Soil Found in Two Hospitals in Bandar Abbas, Iran.
Fungal contamination in hospitals has been a major health concern, especially in immunosuppressed patients. Construction programs increase the risk of fungal contaminations in hospitals. This study aimed to monitor and c...
Study on attitudes of students of Islamic Azad University Tehran Medical Branch toward food safety, 2016
BACKGROUND: Given the importance of high-quality healthy food for humans, contamination control is the most important concern for healthy staff. AIM: To determine the attitudes of students at Islamic Azad University (Te...
Environmental interventions based on the Health Belief Model and the Ecological-social model in the continuation of consumption of rice, free from toxic metals
BACKGROUND AND AIM: Continuation of healthy nutritional behaviors is one of the important factors in effectiveness of educational intervention programs. The aim of this research is to compare the Health Belief Model and...
Effects of dexmedetomidine on heart arrhythmia prevention in off-pump coronary artery bypass surgery: A randomized clinical trial
BACKGROUND: Arrhythmia occurring during and after surgery is one of the major complications in open-heart surgery. Dexmedetomidine is an intravenous alpha-2 agonist and very specific short-acting drug to protect the vari...