MORAXELLA OSLOENSIS MEDIATED SYNTHESIS OF TIO2 NANOPARTICLES

Abstract

Objective: The main idea behind the present investigation is to explore the ability of Moraxella osloensis to reduce Titanium dioxide to nanosizes in a facile manner.Methods: The bacterium was grown in nutrient broth for 24 hr. The culture supernant was used for the bioreduction process. The synthesized nanoparticles were characterised by instrumental analyses namely FTIR, SEM and XRD. Toxicity of the nanoparticles was tested against HaCaT and Hep2 cell lines.Results: Moraxella osloensis with the dye degrading ability was found to be capable of reducing bulk Titanium dioxide to nanostructure. These biogenic TiO2 nanoparticles (TiO2 NPs) were in the size range of 60–150 nm with the average size of 72 nm. The particles were found to irregularly shaped and uniformly dispersed with less aggregation. In addition, XRD analysis indicated the presence of titanium beta. FTIR confirmed the involvement of proteins in the bioreduction and stabilization. Nano TiO2 was found to be more toxic against HaCaT and Hep2 cell lines than its bulk counterpart.Conclusion: Moraxella osloensis successfully synthesised TiO2 NPs in environmentally safe and cost effective method in an extracellular fashion.Keywords: Moraxella osloensis, Biogenesis, TiO2 NP, Characterization, Cytotoxicity

Authors and Affiliations

Valli Nachiyar C. , Vijayalakshmi R. , Nivedha Kumar, Bavanilatha M. , Swetha Sunkar

Keywords

Related Articles

DESIGN AND OPTIMIZATION OF DOXORUBICIN HCL PRONIOSOMES BY-DESIGN OF EXPERIMENT

Objective: The present research work was designed to formulate and optimize doxorubicin HCl proniosomes by design of experiment (DoE). Methods: A 4-factor, 3-level Box-Behnken design was used to explain multiple linear...

IN SILICO MOLECULAR DOCKING AND PHARMACOKINETIC PREDICTION OF GALLIC ACID DERIVATIVES AS PPAR-γ AGONISTS

Objective: To perform molecular docking and pharmacokinetic prediction of gallic acid derivatives as Peroxisome proliferator-activated receptors-γ (PPAR-γ) agonist for the treatment of diabetes.Methods: Molecular docki...

ATTENUATION OF ANTINOCICEPTIVE EFFECT OF MORPHINE IN DIABETIC MICE: NITRIC OXIDE OR INTERLEUKIN-2

Objective: The present study was designed to explore the mechanistic role of interleukin-2 in diabetes-induced decrease in the antinociceptive effect of morphine in mice. Role of interleukin-2 was investigated by employi...

EXTRACTION, ISOLATION AND IDENTIFICATION OF PHYTOCONSTITUENTS PRESENT IN THE HEMIONITIS ARIFOLIA LEAVES

Objective: The investigation was carried out to prepare 95 and 50% ethanol extract of Hemionitis arifolia leaves, and for the identification and quantification of the phytoconstituents present in it.Methods: Soxhlet extr...

AQUEOUS LEAF EXTRACT OF CARICA PAPAYA (CARICACEAE) LINN. CAUSES LIVER INJURY AND REDUCED FERTILITY IN RATS

Objective: Dried Carica papaya (Caricaceae) leaves have been used in traditional medicine as a contraceptive. The objective of the present study was to evaluate the safety of the aqueous leaf extract of Carica papaya and...

Download PDF file
  • EP ID EP577669
  • DOI -
  • Views 54
  • Downloads 0

How To Cite

Valli Nachiyar C. , Vijayalakshmi R. , Nivedha Kumar, Bavanilatha M. , Swetha Sunkar (2016). MORAXELLA OSLOENSIS MEDIATED SYNTHESIS OF TIO2 NANOPARTICLES. International Journal of Pharmacy and Pharmaceutical Sciences, 8(5), 397-400. https://europub.co.uk/articles/-A-577669