Morbidity and mortality after implantation of St. Jude medical, bileaflet mechanical heart valve
Journal Title: Journal of Medical Sciences - Year 2015, Vol 18, Issue 1
Abstract
INTRODUCTION: To assess our experience with cardiac valve replacement with the St. Jude Medical bileaflet mechanical heart valve. METHODS: Retrospective and prospective observational study. RESULTS: Between 2003 and 2014, 430 patients underwent single aortic (n = 98), single mitral (n = 229), or double aortic and mitral (n = 103) valve replacement with the St. Jude Medical valve at our hospital. There were 199 male patients and 231 female patients. Ages ranged from 19 to 65 years (mean, 39.16 years). The early mortality rate was 5.5% (25 patients). Follow-up was 94.8% complete. Thirty-six patients died, for a late mortality rate of 9.3%. Twenty-two patients had thromboembolic episodes (1.35/100 patient-years). Seventeen patients (1.05/100 patient-years) had anticoagulant-related hemorrhage, four (0.2/100 patient-years) had prosthetic valve endocarditis, seven (0.4/100 patient-years) had nonstructural valve dysfunction, and four (0.2/100 patient-years) underwent reoperation. The total number of valve-related deaths was 21. The robabilities of freedom from thromboembolism and anticoagulant-related hemorrhage at 12 years were 94.1% and 94.1 in aortic valve replacement, 94.7% and 96.6% in mitral valve replacement, and 93.5% and 94.6% in double valve replacement, respectively. The event-free rate, including all complications and late deaths, at 12 years was 77.6%, 75.36%, and 72.8% in aortic valve replacement, mitral valve replacement, and double valve replacement, respectively. CONCLUSION: The St. Jude Medical valve is an excellent mechanical valve in terms of durability and low thrombogenicity and remains our prosthetic valve of choice when valve replacement with a mechanical valve is indicated.
Authors and Affiliations
Tasneem Muzaffar, GN Lone
Keywords
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