Morphological and Functional Abnormalities of the Thyroid Gland among End Stage Kidney Disease Patients
Journal Title: Journal of Preventive Medicine and Care - Year 2016, Vol 2, Issue 4
Abstract
Several interactions exist between thyroid and kidney function in many disorders. Many publications explored the relationship between thyroid diseases (TD) and chronic kidney diseases (CKD). However, the morphological thyroid changes in patients with CKD or End Stage Kidney disease (ESKD) were not fully explored. The aim of this study is to explore the morphological and the functional abnormalities of the thyroid gland among ESKD patients as detected by Doppler ultrasound. Patients and Methods: All of the 92 ESKD patients at our center were consented and included in the study. Demographic and clinical data and biochemical and hormonal profiles were recorded. Every patient received a dedicated ultrasound scan of the thyroid gland. GE ultrasound system with Doppler capabilities and high frequency transducer was used. Grey scale imaging and Doppler ultrasound were used to image the thyroid gland for every patient. Taking the thyroid morphology detected by ultrasound and the thyroid function as the dependent variables, all other parameters of age, sex, BMI, occupation, residence, duration of time on dialysis and other comorbilities were taken as independent variables and their relationship to the dependent variables was further studied using appropriate statistical tests. Results: Thyroid nodule(s) presence was found to be the most prevalent thyroid morphology detected on ultrasound scanning. Fifty three patients (57.6%) were found to have ultrasound detected nodule(s). The nodule presence was correlated to different independent variables and was found to significantly correlate with age only. The thyroid function as reflected by the level of thyroid hormones was also studied for correlation with the independent variables. No correlation was found between the thyroid function and the presence of nodules. Conclusion and Recommendation: Ultrasound detected nodules are very common in ESKD patients. The presence of nodule significantly correlates with patient age denoting its degenerative nature. Ultrasound screening of the thyroid in ESKD patients may be cost effective. However, we recommend a larger multicenter study for better results.
Authors and Affiliations
Osman O, Alnaemi T, Alneel S, Qayyum F, Abdalla M, Makeen A, Griffith B
Keywords
Related Articles
- EP ID EP250467
- DOI 10.14302/issn.2372-6601.jhor-17-1606
- Views 100
- Downloads 0
One-Third of Patients With Type 2 Diabetes Mellitus Do Not Have Coronary Artery Calcification
Objective Measuring coronary artery calcification (CAC) enables to optimize cardiovascular risk-stratification also in patients with type 2 diabetes mellitus (T2D), however the prevalence of CAC in randomly selected pati...
Early Detection of Post-transplant Lymphoproliferative Disorder by Head and Neck Manifestations
Introduction: Post-transplant lymphoproliferative disease (PTLD) is a collection of conditions associated with abnormal proliferation of lymphoid tissues in patients after solid organ transplants (SOT). Its clinical pre...
Inguinal Hernia: A Probable Complication of Urinary Schistosomiasis in School Age Male Children in an Area Highly Endemic for Schistosoma Haematobium in Zambia.
Introduction Schistosoma haematobium infection is acquired early in life with the peak prevalence and intensity of infection occurring in the second decade of life in endemic areas. The aim of this study was to establis...
Fostering Partnerships between Public Health Functions within Health and Social Services Organizations: A Perspective from the Province of Quebec (Canada)
Health and social services organizations discriminate too much between core public health functions. Health protection actions, services, and programs are often separate from those concerned with disease prevention and h...
A Checklist Instrument: Sensory Cues within Assisted Living Facilities
As people age, environments supporting changing needs can potentially impact their quality of life. The purpose of this exploratory study was to develop and assess the validity of a checklist instrument used to evaluate...