Mould fungi and the role of allergy on fungi in chronic rhinosinusitis
Journal Title: Otolaryngologia Polska - Year 2009, Vol 63, Issue 3
Abstract
Aim: The aim of this work was to assessment the role of mould fungi and the allergy on fungi in chronic rhinosinusitis. Material and methods: We studied 30 patients with chronic rhinosinusitis with or without polyposis who underwent endoscopic nose and sinuses procedures. Clinical and immunological workup was performed for atopy in all patients. We performed CT of the sinuses, skin – prick testing on 15 fungal allergens , total IgE and fungal-specific IgE levels, eosinophilia level. Specimens were sent for mycology and histopathologic analysis for identyfi cation of fungi. Results: Fungal culture from sinuses were negative in all patients. Bacterial culture were positive in 19 cases. There was observed elevated total immunoglobulin E level in 70 % of patients. Positive skin test reactivity for fungal allergen was observed in 7 patients – 3 for Aspergillus, 2 for Alternaria and 2 for Cladosporium. Fungal specific IgE levels were below 0,35 KU/L in all patients. Nasal polyps were found in 26 patients, they were associated with asthma and aspirin intollerance. No fungal hyphae were found in histopathologic analysis. Conclusions: Our preliminary study suggest, that allergy for fungi doesn’t play a significant role in etiology and pathogenesis of the chronic rhinosinusitis with or without polyps. We did’t find any case of the allergic fungal sinusitis in our patients.
Authors and Affiliations
Małgorzata Różańska-Kudelska, Andrzej Sieśkiewicz, Barbara Południewska, Magdalena Kania, Izabela Michalczuk, Marek Rogowski
Keywords
Related Articles
- EP ID EP51740
- DOI -
- Views 106
- Downloads 0
The healing process of tympanic membrane perforations in rats
The aim of the study was otoscopical and histological evaluation of the rat's TM healing process. Material and methods : 56 male Wistar rats were used for the study. Fifty of them had TMs perforated bilaterally using CO2...
Ostre izolowane zapalenie zatoki klinowej – opis 4 przypadków
Introduction: Isolated acute sphenoid sinusitis is an uncommon sinus infection, frequently misdiagnosed and not usually considered in the differential diagnosis of acute severe headache, with the potential of serious neu...
Wywołane słuchowe potencjały stanu ustalonego (ASSR – auditory steady-state responses), dotychczasowy stan wiedzy
The auditory steady-state responses (ASSR) is quite a new method of electrophysiological threshold estimation with no clinical standards. It was the aim of this study to review practical and theoretical thesis of ASSR an...
Ocena jakości życia przed i po septorynoplastyce metodą otwartą przy użyciu ankiety WHOQOL-BREF
Wprowadzenie: Celem pracy była ocena wpływu plastyki nosa na jakość różnych aspektów życia. Badaniem objęto 79 pacjentów z pourazowymi lub wrodzonymi deformacjami nosa (38 mężczyzn, 41 kobiet) w wieku od 17 do 49 lat (śr...
Postoperative bone conduction thresholds changes in patients operated on chronic otitis media – analysis
Background: Postoperative hearing improvement is measured as Air-Bone gap changes. Changes in bone conduction threasholds as a results of otosurgery is also discussed. Aim: We discuss factors that have influence on bone...