Mucormycosis in diabetes mellitus
Journal Title: Journal of Advances in Internal Medicine - Year 2012, Vol 1, Issue 2
Abstract
Mucormycosis is an opportunistic fulminant fungal infection, which mainly infects immunocompromised patients. Infection with mucormycosis can cause devastating rhino-orbital-cerebral and pulmonary infection with an extremely poor prognosis. The infection begins in the nose and paranasal sinuses due to inhalation of fungal spores. We report a case of mucormycosis in an uncontrolled diabetic patient to emphasize early diagnosis of this potentially fatal fungal infection. Rhino-orbitalcerebral mucormycosis is the most common manifestation in patients with diabetes mellitus. We also review the current concepts in management of mucormycosis. Mucormycosis remains difficult to treat and requires a multifaceted approach involving elimination of predisposing factors, surgical debridement, and anti-fungal therapy. Lipid formulations of Amphotericin B are the treatments of choice.
Authors and Affiliations
Prashant Khatiwada*| Kathmandu University School of Medical Sciences, Dhulikhel, Nepal, Aditi Giri| Kathmandu University School of Medical Sciences, Dhulikhel, Nepal, Prasana Khatiwoda| Richa Bajimaya Memorial Foundation, Kathmandu, Nepal
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